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首页> 美国卫生研究院文献>AIDS Patient Care and STDs >Behavioral Health Risks in Perinatally HIV-Exposed Youth: Co-Occurrence of Sexual and Drug Use Behavior Mental Health Problems and Nonadherence to Antiretroviral Treatment
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Behavioral Health Risks in Perinatally HIV-Exposed Youth: Co-Occurrence of Sexual and Drug Use Behavior Mental Health Problems and Nonadherence to Antiretroviral Treatment

机译：周围感染艾滋病毒的青年人的行为健康风险：性和药物使用行为心理健康问题和不坚持抗逆转录病毒治疗的共同发生

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In a sample of perinatally HIV-infected (PHIV+) and perinatally HIV-exposed, uninfected (PHEU) adolescents, we examined the co-occurrence of behavioral health risks including mental health problems, onset of sexual and drug use behaviors, and (in PHIV+ youth) nonadherence to antiretroviral therapy (ART). Participants, recruited from 2007 to 2010, included 349 youth, ages 10–16 years, enrolled in a cohort study examining the impact of HIV infection and ART. Measures of the above behavioral health risks were administered to participants and primary caregivers. Nearly half the participants met study criteria for at least one behavioral health risk, most frequently, mental health problems (28%), with the onset of sexual activity and substance use each reported by an average of 16%. Among the sexually active, 65% of PHIV+ and 50% of PHEU youth reported unprotected sex. For PHIV +youth, 34% reported recent ART nonadherence, of whom 45% had detectable HIV RNA levels. Between 16% (PHIV+) and 11% (PHEU) of youth reported at least two behavioral health risks. Older age, but not HIV status, was associated with having two or more behavioral health risks versus none. Among PHIV+ youth, living with a birth mother (versus other caregivers) and detectable viral load were associated with co-occurrence of behavioral health risks. In conclusion, this study suggests that for both PHIV+ and PHEU youth, there are multiple behavioral health risks, particularly mental health problems, which should be targeted by service systems that can integrate prevention and treatment efforts.
机译：在围产期感染HIV（PHIV +）和围产期暴露HIV，未感染（PHEU）的青少年样本中，我们检查了行为健康风险的同时存在，包括心理健康问题，性行为和吸毒行为的发作，以及（在PHIV +青年）不坚持抗逆转录病毒疗法（ART）。从2007年至2010年招募的参与者包括349名10至16岁的青年，他们参加了一项队列研究，研究了HIV感染和ART的影响。对参与者和初级护理人员进行了上述行为健康风险的衡量。将近一半的参与者符合至少一项行为健康风险的研究标准，其中最常见的是精神健康问题（28％），据报道性行为和药物使用的发生率平均为16％。在性活跃者中，有65％的PHIV +和50％的PHEU青年报告说没有保护性行为。对于PHIV +青年，有34％的人报告了近期抗病毒治疗的不依从性，其中45％的人可检测到HIV RNA水平。在16％（PHIV +）和11％（PHEU）的青年中，至少有两个行为健康风险。年龄较大，但没有艾滋病毒感染，则有两个或更多的行为健康风险，而没有风险。在PHIV +青年中，与分娩母亲（与其他照料者）一起生活和可检测的病毒载量与行为健康风险的共同发生有关。总之，这项研究表明，对于PHIV +和PHEU青年，都存在多种行为健康风险，尤其是精神健康问题，应由能够将预防和治疗工作结合起来的服务系统来应对。

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