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P-021Tanshinone IIA can inhibit human pancreatic carcinoma BxPC3 cells through decreasing the protein expressions of IGFR EGFR VEGFR and blocking both Ras/Raf/MEK/ERK and Ras/PI3K/AKT/mTOR pathway in vitro and in vivo

机译：P-021丹参酮IIA可以通过降低IGFREGFRVEGFR的蛋白质表达并阻断Ras / Raf / MEK / ERK和Ras / PI3K / AKT / mTOR通路来抑制人胰腺癌BxPC3细胞

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期刊名称 Annals of Oncology
作者
C.C. Su;
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作者单位

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年(卷),期 -1(27),Suppl 2
年度 -1
页码 ii7
总页数 1
原文格式 PDF
正文语种
中图分类肿瘤学;
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专利

1. Tanshinone IIA decreases the protein expression of EGFR, and IGFR blocking the PI3K/Akt/mTOR pathway in gastric carcinoma AGS cells both in vitro and in vivo [J] . Su Chin-Cheng, Chiu Tsung-Lang Oncology reports . 2016,第2期

机译：丹参酮IIA可以在体内外降低胃癌AGS细胞中EGFR的蛋白表达和IGFR阻断PI3K / Akt / mTOR通路
2. Tanshinone IIA can inhibit MiaPaCa-2 human pancreatic cancer cells by dual blockade of the Ras/Raf/MEK/ERK and PI3K/AKT/mTOR pathways [J] . Su Chin-Cheng Oncology reports . 2018,第5期

机译：丹参酮IIA可以通过双封闭RAS / RAF / MEK / ERK和PI3K / AKT / MTOR途径抑制Miapaca-2人胰腺癌细胞
3. Tanshinone IIA inhibits gastric carcinoma AGS cells by decreasing the protein expression of VEGFR and blocking Ras/Raf/MEK/ERK pathway [J] . Su Chin-Cheng International journal of molecular medicine . 2018,第4期

机译：丹参酮IIA通过降低VEGFR和阻断RAS / RAF / MEK / ERK途径的蛋白质表达来抑制胃癌AGS细胞
4. M2-A, A Novel Amonafide Analogue, Induces Apoptosis and G2-M Arrest via Decreasing Topoisomerase LIa Activity and Inhibits PI3K/Akt Pathway on HL60 Cells [C] . The 12th Asian Pacific Confederation of Chemical Engineering Congress(第十二届亚太化工联盟大会暨化工展览会)论文集 . 2008

机译：M2-A，一种新颖的阿莫那肽类似物，通过降低拓扑异构酶LIa活性诱导HL60细胞凋亡和G2-M逮捕并抑制PI3K / Akt途径。
5. FGF8 regulates patterning and gene expression in the neocortical primordium through both the MEK/ERK and PI3K/AKT signal transduction cascades. [D] . Gulden, Forrest O. 2014

机译：FGF8通过MEK / ERK和PI3K / AKT信号转导级联调节新皮质原基中的模式和基因表达。
6. Dual blockade of the PI3K/AKT/mTOR (AZD8055) and RAS/MEK/ERK (AZD6244) pathways synergistically inhibits rhabdomyosarcoma cell growth in vitro and in vivo [O] . Jane Renshaw, Kathryn R. Taylor, Ryan Bishop, -1

机译：PI3K / AKT / mTOR（AZD8055）和RAS / MEK / ERK（AZD6244）通路的双重阻断在体外和体内均协同抑制横纹肌肉瘤细胞的生长
7. Tanshinone IIA can inhibit MiaPaCa‑2 human pancreatic cancer cells by dual blockade of the Ras/Raf/MEK/ERK and PI3K/AKT/mTOR pathways [O] . Chin‑Cheng Su 2018

机译：丹参酮IIa可以通过RAS / RAF / MEK / ERK和PI3K / AKT / MTOR途径的双封闭式抑制MIAPACA-2人胰腺癌细胞

P-021Tanshinone IIA can inhibit human pancreatic carcinoma BxPC3 cells through decreasing the protein expressions of IGFR EGFR VEGFR and blocking both Ras/Raf/MEK/ERK and Ras/PI3K/AKT/mTOR pathway in vitro and in vivo

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