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Realizing Our Potential in Biobanking: Disease Advocacy Organizations Enliven Translational Research

机译:发挥我们在生物银行中的潜力:疾病倡导组织活跃着转化研究

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摘要

Biobanks are increasingly powerful tools used in translational research, and disease advocacy organizations (DAOs) are making their presence known as research drivers and partners. We examined DAO approaches to biobanking to inform how the enterprise of biobanking can grow and become even more impactful in human health. In this commentary, we outline overarching approaches from successful DAO biobanks. These lessons learned suggest principles that can create a more participant-centric approach and illustrate the key roles DAOs can play as partners in research initiatives. DAO approaches to biobanking for translational research include the following: be outcome driven; forge alliances that are unexpected—build bridges to enhance translation; come ready for success; be nimble, flexible, and adaptable; and remember that people matter. Each of these principles led to particular practices that have increased the translational impact of biobank collections. The research practices discussed can inform partnerships in all sectors going forward.
机译:生物库是转化研究中越来越强大的工具,而疾病倡导组织(DAO)则将其存在称为研究推动者和合作伙伴。我们研究了DAO的生物银行方法,以告知生物银行企业如何成长并变得对人类健康更具影响力。在这篇评论中,我们概述了成功的DAO生物库的总体方法。这些经验教训提出了一些原则,这些原则可以创建一种以参与者为中心的方法,并说明DAO在研究计划中可以充当合作伙伴的关键角色。 DAO进行转化研究的生物库方法包括:以结果为导向;建立意想不到的联盟-建立桥梁以增强翻译;为成功做好准备;敏捷,灵活和适应能力强;并记住,人很重要。这些原则中的每一个都导致了特殊的实践,这些实践增加了生物库集合的翻译影响。讨论的研究实践可以为今后所有领域的合作伙伴提供信息。

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