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The ONCO-I2b2 Project: Integrating Biobank Information and Clinical Data to Support Translational Research in Oncology

机译:ONCO-I2B2项目:集成BIOBANK信息和临床数据,以支持肿瘤学的翻译研究

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The University of Pavia and the IRCCS Fondazione Salvatore Maugeri of Pavia (FSM), has recently started an IT initiative to support clinical research in oncology, called ONCO-i2b2. ONCO-i2b2, funded by the Lombardia region, grounds on the software developed by the Informatics for Integrating Biology and the Bedside (i2b2) NIH project. Using i2b2 and new software modules purposely designed, data coming from multiple sources are integrated and jointly queried. The core of the integration process stands in retrieving and merging data from the biobank management software and from the FSM hospital information system. The integration process is based on a ontology of the problem domain and on open-source software integration modules. A Natural Language Processing module has been implemented, too. This module automatically extracts clinical information of oncology patients from unstructured medical records. The system currently manages more than two thousands patients and will be further implemented and improved in the next two years.
机译:帕维亚大学和帕维亚IRCCS基金会的Salvatore Maugeri(FSM),最近开始的IT计划,以支持在肿瘤学临床研究,所谓的致癌i2b2。由Lombardia地区资助的ONCO-I2B2,在信息学界限开发的软件,用于整合生物学和床头柜(I2B2)NIH项目。使用I2B2和新的软件模块故意设计,来自多个来源的数据集成并共同查询。集成过程的核心站在从BioBank管理软件和FSM医院信息系统中检索和合并。集成过程基于问题域和开源软件集成模块的本体。也实现了一种自然语言处理模块。该模块自动提取来自非结构化病程的肿瘤患者的临床信息。该系统目前管理超过两千名患者,并将在未来两年进一步实施和改善。

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