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Community effort endorsing multiscale modelling multiscale data science and multiscale computing for systems medicine

机译：社区努力支持系统医学的多尺度建模多尺度数据科学和多尺度计算

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摘要

Systems medicine holds many promises, but has so far provided only a limited number of proofs of principle. To address this road block, possible barriers and challenges of translating systems medicine into clinical practice need to be identified and addressed. The members of the European Cooperation in Science and Technology (COST) Action CA15120 Open Multiscale Systems Medicine (OpenMultiMed) wish to engage the scientific community of systems medicine and multiscale modelling, data science and computing, to provide their feedback in a structured manner. This will result in follow-up white papers and open access resources to accelerate the clinical translation of systems medicine.

机译：系统医学具有许多前景，但到目前为止仅提供了数量有限的原理证明。为了解决这一障碍，需要确定并解决将系统医学转化为临床实践的可能障碍和挑战。欧洲科学技术合作（COST）行动CA15120开放式多尺度系统医学（OpenMultiMed）的成员希望与系统医学和多尺度建模，数据科学和计算科学界合作，以结构化的方式提供反馈。这将产生后续白皮书和开放获取资源，以加速系统医学的临床翻译。

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期刊名称 Briefings in Bioinformatics
作者
Massimiliano Zanin; Ivan Chorbev; Blaz Stres; Egils Stalidzans; Julio Vera; Paolo Tieri; Filippo Castiglione; Derek Groen; Huiru Zheng; Jan Baumbach; Johannes A Schmid; José Basilio; Peter Klimek; Nataša Debeljak; Damjana Rozman; Harald H H W Schmidt;
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作者单位

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年(卷),期 -1(20),3
年度 -1
页码 1057–1062
总页数 6
原文格式 PDF
正文语种
中图分类生化遗传学;生化药理学;
关键词
systems medicine modelling data science computing;

机译：系统医学;建模;数据科学;计算;

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专利

1. Community effort endorsing multiscale modelling, multiscale data science and multiscale computing for systems medicine [J] . Massimiliano Zanin, Ivan Chorbev, Blaz Stres, Briefings in bioinformatics . 2019,第3期

机译：社区努力认可多尺度建模，多尺度数据科学和系统医学的多尺度计算
2. Corresponding author. Joel T. Dudley, Institute for Next Generation Healthcare, Department of Genetics and Genomic Sciences, Icahn Institute for Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, Mount Sinai Health System New York, NY; E-mail: joel.dudley@mssm.edu [J] . Francesca Finotello, Eleonora Mastrorilli, Barbara Di Camillo Briefings in bioinformatics . 2018,第4期

机译：通讯作者。 Joel T. Dudley，下一代医疗教育学院，遗传学和基因组科学系，ICAHN基因组学院和多尺度生物学研究所，ICAHN Mount Sinai Mount Sinai Health System纽约州纽约州纽约山区纽约; 电子邮件：joel.dudley@mssm.edu
3. Materials integrity in microsystems: a framework for a petascale predictive-science-based multiscale modeling and simulation system [J] . To AC, Liu WK, Olson GB, Computational Mechanics: Solids, Fluids, Fracture Transport Phenomena and Variational Methods . 2008,第4期

机译：微系统中的材料完整性：基于Petascale预测科学的多尺度建模和仿真系统的框架
4. A review of multiscale science: Materials, biology, multiscale data analysis and examples from complex physiological systems [C] . Jiaqi Liang IEEE International Conference on Mechatronics and Automation . 2017

机译：多尺度科学回顾：材料，生物学，多尺度数据分析和来自复杂生理系统的例子
5. Modeling Daily Ambient Air Pollution Using Community Multiscale Air Quality (CMAQ) System [D] . ?Jiang, Xiangyu 2020

机译：使用社区多尺度空气质量（CMAQ）系统建模日常环境空气污染
6. Molecular systems biology of ErbB1 signaling: bridging the gap through multiscale modeling and high-performance computing [O] . Andrew J. Shih, Jeremy Purvis, Ravi Radhakrishnan -1

机译：ErbB1信号传导的分子系统生物学：通过多尺度建模和高性能计算弥合差距
7. Final Report. DOE Computational Nanoscience Project DE-FG02-03ER46096: Integrated Multiscale Modeling of Molecular Computing Devices [O] . Cummings, Peter 2009

机译：总结报告。 DOE计算纳米科学项目DE-FG02-03ER46096：分子计算设备的集成多尺度建模
8. Science Features in Models-3 Community Multiscale Air Quality System [R] . Ching, J., Byun, D., Young, J., 1997

机译：模型-3社区多尺度空气质量系统的科学特征

Community effort endorsing multiscale modelling multiscale data science and multiscale computing for systems medicine

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