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首页> 美国卫生研究院文献>Scientific Reports >Curved Beam Computed Tomography based Structural Rigidity Analysis of Bones with Simulated Lytic Defect: A Comparative Study with Finite Element Analysis
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Curved Beam Computed Tomography based Structural Rigidity Analysis of Bones with Simulated Lytic Defect: A Comparative Study with Finite Element Analysis

机译：基于弯曲束计算机断层扫描的模拟胶体缺陷的结构刚度分析：有限元分析的比较研究

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摘要

In this paper, a CT based structural rigidity analysis (CTRA) method that incorporates bone intrinsic local curvature is introduced to assess the compressive failure load of human femur with simulated lytic defects. The proposed CTRA is based on a three dimensional curved beam theory to obtain critical stresses within the human femur model. To test the proposed method, ten human cadaveric femurs with and without simulated defects were mechanically tested under axial compression to failure. Quantitative computed tomography images were acquired from the samples, and CTRA and finite element analysis were performed to obtain the failure load as well as rigidities in both straight and curved cross sections. Experimental results were compared to the results obtained from FEA and CTRA. The failure loads predicated by curved beam CTRA and FEA are in agreement with experimental results. The results also show that the proposed method is an efficient and reliable method to find both the location and magnitude of failure load. Moreover, the results show that the proposed curved CTRA outperforms the regular straight beam CTRA, which ignores the bone intrinsic curvature and can be used as a useful tool in clinical practices.
机译：本文介绍了一种基于CT的结构刚度分析（CTRA）方法，该方法结合了骨固有的局部曲率，以评估具有模拟溶解缺陷的人股骨的压缩破坏负荷。提出的CTRA基于三维弯曲梁理论来获得人股骨模型内的临界应力。为了测试所提出的方法，在轴向压缩至失效的情况下，机械测试了十个具有和没有模拟缺陷的人尸体股骨。从样品中获取定量的计算机断层扫描图像，并进行CTRA和有限元分析以获取破坏载荷以及笔直和弯曲截面的刚度。将实验结果与从FEA和CTRA获得的结果进行比较。由弯曲梁CTRA和FEA预测的破坏载荷与实验结果一致。结果还表明，所提出的方法是一种有效且可靠的方法，可以同时找到失效载荷的位置和大小。此外，结果表明，提出的弯曲CTRA优于常规的直光束CTRA，后者忽略了骨的内在曲率，可在临床实践中用作有用的工具。

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