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Hormesis and homeopathy: The artificial twins

机译:兴奋和顺势疗法:人工双胞胎

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摘要

Homeopathy claims a curative reaction from small doses of a substance, high doses of which cause symptoms similar to those the patient is suffering from. Hormesis is a concept of biphasic dose-response to different pharmacological and toxicological agents. According to this concept, a small dose of a noxious agent can exert a beneficial action. A hypothesis is defended here that hormesis as a general principle can be assumed only for the factors present in the natural environment thus having induced adaptation of living organisms. Generalizations of the hormesis phenomenon used in support of homeopathy are unfounded. Low-dose impacts may be associated with a higher risk in a state of organ sub-compensation or failure especially in the elderly patients. Practical recommendations should be based neither on the hormesis as a default approach nor on the postulates of homeopathy. All clinically relevant effects, hormetic or not, should be tested by the methods of evidence-based medicine.
机译:顺势疗法要求小剂量物质产生治愈反应,大剂量物质引起的症状与患者所患症状相似。兴奋剂是对不同药理和毒理学试剂的双相剂量反应的概念。根据该概念,小剂量的有害物质可以发挥有益作用。这里有一个假说,即只有在自然环境中存在的因素才能假定激素是总的原理,因此引起了活生物体的适应。用于支持顺势疗法的兴奋剂现象的概括尚无根据。低剂量的影响可能与器官亚补偿或衰竭状态下的较高风险相关,尤其是在老年患者中。实用的建议既不应基于作为默认方法的兴奋剂,也不应基于顺势疗法的假设。所有临床相关的影响,无论是否有震颤,都应通过循证医学的方法进行测试。

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