首页> 美国卫生研究院文献>EURASIP Journal on Bioinformatics and Systems Biology >Review of stochastic hybrid systems with applications in biological systems modeling and analysis
【2h】

Review of stochastic hybrid systems with applications in biological systems modeling and analysis

机译:综述随机混合系统及其在生物系统建模和分析中的应用

代理获取
本网站仅为用户提供外文OA文献查询和代理获取服务,本网站没有原文。下单后我们将采用程序或人工为您竭诚获取高质量的原文,但由于OA文献来源多样且变更频繁,仍可能出现获取不到、文献不完整或与标题不符等情况,如果获取不到我们将提供退款服务。请知悉。

摘要

Stochastic hybrid systems (SHS) have attracted a lot of research interests in recent years. In this paper, we review some of the recent applications of SHS to biological systems modeling and analysis. Due to the nature of molecular interactions, many biological processes can be conveniently described as a mixture of continuous and discrete phenomena employing SHS models. With the advancement of SHS theory, it is expected that insights can be obtained about biological processes such as drug effects on gene regulation. Furthermore, combining with advanced experimental methods, in silico simulations using SHS modeling techniques can be carried out for massive and rapid verification or falsification of biological hypotheses. The hope is to substitute costly and time-consuming in vitro or in vivo experiments or provide guidance for those experiments and generate better hypotheses.
机译:近年来,随机混合系统(SHS)吸引了许多研究兴趣。在本文中,我们回顾了SHS在生物系统建模和分析中的一些最新应用。由于分子相互作用的性质,使用SHS模型可以方便地将许多生物过程描述为连续现象和离散现象的混合体。随着SHS理论的发展,人们有望获得有关生物学过程的见解,例如药物对基因调控的影响。此外,结合先进的实验方法,可以使用SHS建模技术进行计算机模拟,以大规模,快速地验证或伪造生物学假设。希望替代昂贵且费时的体外或体内实验,或为这些实验提供指导并产生更好的假设。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
代理获取

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号