I12'/> Monte Carlo calculations and experimental measurements of the TG‐43U1‐recommended dosimetric parameters of 125I (Model IR‐Seed2) brachytherapy source
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 美国卫生研究院文献>Journal of Applied Clinical Medical Physics >Monte Carlo calculations and experimental measurements of the TG‐43U1‐recommended dosimetric parameters of 125I (Model IR‐Seed2) brachytherapy source
【2h】

Monte Carlo calculations and experimental measurements of the TG‐43U1‐recommended dosimetric parameters of 125I (Model IR‐Seed2) brachytherapy source

机译：TG-43U1推荐的125I（IR-Seed2型）近距离放射治疗源剂量参数的蒙特卡洛计算和实验测量

代理获取
本网站仅为用户提供外文OA文献查询和代理获取服务，本网站没有原文。下单后我们将采用程序或人工为您竭诚获取高质量的原文，但由于OA文献来源多样且变更频繁，仍可能出现获取不到、文献不完整或与标题不符等情况，如果获取不到我们将提供退款服务。请知悉。
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

A new design of I125 (Model IR‐Seed2) brachytherapy source has been manufactured recently at the Applied Radiation Research School, Nuclear Science and Technology Research Institute in Iran. The source consists of six resin beads (0.5 mm diameter) that are sealed in a cylindrical titanium capsule of 0.7 mm internal and 0.8 mm external diameters. This work aims to evaluate the dosimetric parameters of the newly designed I125 source using experimental measurements and Monte Carlo (MC) simulations. Dosimetric characteristics (dose rate constant, radial dose function, and 2D and 1D anisotropy functions) of the IR‐Seed2 were determined using experimental measurements and MC simulations following the recommendations by the Task Group 43 (TG‐43U1) report of the American Association of Physicists in Medicine (AAPM). MC simulations were performed using the MCNP5 code in water and Plexiglas, and experimental measurements were carried out using thermoluminescent dosimeters (TLD‐GR207A) in Plexiglas phantoms. The measured dose to water in Plexiglas data were used for verification of the accuracy of the source and phantom geometry in the Monte Carlo simulations. The final MC simulated data to water in water were recommended for clinical applications. The MC calculated dose rate constant (Λ) of the IR‐Seed2 I125 seed in water was found to be 0.992 ± 0.025 cGy h−1U−1. Additionally, its radial dose function by line and point source approximations, gL(r) and gp(r), calculated for distances from 0.1 cm to 7 cm. The values of gL(r) at radial distances from 0.5 cm to 5 cm were measured in a Plexiglas phantom to be between 1.212 and 0.413. The calculated and measured of values for 2D anisotropy function, F(r, θ), were obtained for the radial distances ranging from 1.5 cm to 5 cm and angular range of 0°‐90° in a Plexiglas phantom. Also, the 2D anisotropy function was calculated in water for the clinical application. The results of these investigations show that the uncertainty of the experimental data is within ±7% between the measured and simulated data in Plexiglas. Based on these results, the MC‐simulated dosimetric parameters of the new I125 source model in water are presented for its clinical applications in brachytherapy treatments.PACS number(s): 87.56.bg
机译： I 125 （IR-Seed2型） ）近距离放射治疗源最近在伊朗核科学技术研究所应用辐射研究所生产。光源由六个树脂珠（直径为0.5毫米）组成，密封在一个内径为0.7毫米，外径为0.8毫米的圆柱形钛容器中。这项工作旨在评估新设计的 我 125 < / math>来源，使用实验测量结果和蒙特卡洛（MC）模拟。遵循美国研究会第43任务组（TG-43U1）报告的建议，通过实验测量和MC模拟确定IR-Seed2的剂量学特征（剂量率常数，径向剂量函数以及2D和1D各向异性函数）。医学物理学家（AAPM）。在水和有机玻璃中使用MCNP5代码进行MC模拟，并在有机玻璃体模中使用热发光剂量计（TLD-GR207A）进行实验测量。在有机玻璃数据中测得的水剂量用于验证蒙特卡洛模拟中光源和体模几何形状的准确性。建议将最终的MC模拟数据转化为水以用于临床。 MC计算的IR-Seed2 我 125 的水中种子为0.992±0.025 cGy h -1 U -1 。此外，它的径向剂量函数由线和点源近似值gL（r）和gp（r）计算得出，计算距离为0.1 cm至7 cm。在有机玻璃体模中，径向距离为0.5 cm至5 cm的gL（r）值在1.212至0.413之间。在有机玻璃体模中，从1.5 cm到5 cm的径向距离和0°-90°的角度范围获得了2D各向异性函数F（r，θ）的值的计算和测量值。此外，还针对临床应用在水中计算了二维各向异性函数。这些调查的结果表明，在有机玻璃中，实验数据的不确定性在实测数据与模拟数据之间在±7％之内。根据这些结果，新的 我 125 源模型在近距离放射治疗中的临床应用。PACS号：87.56.bg

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
代理获取

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号