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Translational research policies: disruptions and continuities in biomedical innovation systems in Austria Finland and Germany

机译:转化研究政策:奥地利芬兰和德国的生物医学创新系统的破坏和连续性

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摘要

Increasing the rate of biomedical research that is relevant to clinical innovation has been an intensifying concern of the research community and of policy-makers. In response, some of these actors have recently promoted varied approaches they label as translational research (TR) and translational medicine. This movement started in the USA in the early 1990s, and has since evolved to encompass large and ambitious initiatives. Its advocates contend that the productivity of biomedical innovation systems can be bolstered by: (1) the extension of large-scale development collaborations; (2) the strengthening of clinical experimental platforms; (3) training and supporting dedicated human capital; (4) achieving higher collective coordination of research teams than was previously common practice. In this paper, we examine to which extent these objectives have been put into practice by communities of biomedical actors and policymakers, by characterizing current translational initiatives in three European countries—Austria, Finland and Germany. This research draws on an analysis of policy documents and 26 semi-structured interviews conducted with policy-makers and TR advocates from these countries. Traditions of science and technology policy-making in each country have made them differentially receptive to the TR movement. German biomedical actors have most fully put into practice TR propositions, while Finland has seen policy-level debate of the notions but little in the way of concrete implementation and Austria appears to be a middle case.
机译:与临床创新相关的生物医学研究速度的提高已成为研究界和决策者日益关注的问题。作为回应,这些行为者中的一些最近促进了被他们标记为翻译研究(TR)和转化医学的多种方法。这项运动始于1990年代初期的美国,此后逐渐演变为涵盖了雄心勃勃的倡议。它的倡导者认为,生物医学创新系统的生产力可以通过以下方式得到提高:(1)扩大大规模发展合作; (2)加强临床实验平台; (三)培训和支持专门的人力资本; (4)与以前的惯例相比,实现研究团队更高的集体协调。在本文中,我们通过描述三个欧洲国家(奥地利,芬兰和德国)目前的翻译计划,来研究生物医学参与者和政策制定者在何种程度上实现了这些目标。这项研究基于对政策文件的分析以及与这些国家的政策制定者和TR倡导者进行的26次半结构化访谈。各国的科学技术决策传统使他们对TR运动的接受程度有所不同。德国的生物医学参与者已将TR建议最充分地付诸实践,而芬兰已经在概念上对概念进行了辩论,但具体实施的方式很少,奥地利似乎处于中间位置。

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