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首页> 美国卫生研究院文献>The Journal of General Physiology >The Nature of the In Vivo Sodium and Chloride Uptake Mechanisms through the Epithelium of the Chilean Frog Calyptocephalella gayi (Dum. et Bibr. 1841)
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The Nature of the In Vivo Sodium and Chloride Uptake Mechanisms through the Epithelium of the Chilean Frog Calyptocephalella gayi (Dum. et Bibr. 1841)

机译：通过智利蛙盖利头孢菌上皮的上皮吸收钠和氯化物的机制的本质（Dum。et Bibr。1841）

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摘要

The Chilean frog, Calyptocephallela gayi, placed in dilute NaCl solutions may pump Na+ and Cl- at very different rates depending on the kind of bath solutions in which it was preadapted. Furthermore, Na+ and Cl- may be absorbed from solutions in which the accompanying coion, such as sulfate and choline, respectively, is impermeant. In all these cases it is obligatory to postulate the existence of two ionic exchange mechanisms, Cl- and Na+, being exchanged against endogenous anions and cations, respectively. It has been determined that Na+ is exchanged against endogenous H+ and that Cl- is exchanged against HCO3 -. In animals pumping Na+ and Cl- from dilute NaCl solutions Na+ or Cl- uptake may be selectively inhibited, while the flux of the accompanying ion remains unchanged. This is considered to be an additional proof that both Na+ and Cl- fluxes are always independent. The role of the ionic exchange mechanisms in the direct regulation of the Na+ and Cl- levels in the internal medium is discussed as well as their relationship in the regulation of the acid-base equilibrium; other physioecological considerations have been treated.
机译：放在稀NaCl溶液中的智利青蛙Calyptocephallela gayi可能会根据预先适应的浴液种类，以非常不同的速率泵送Na + 和Cl -。此外，Na + 和Cl -可能会从溶液中吸收，而伴随的离子，例如硫酸盐和胆碱，是不可渗透的。在所有这些情况下，必须假定存在两种离子交换机制，分别是Cl -和Na + 与内源性阴离子和阳离子交换。已确定Na + 与内源性H + 交换，而Cl -与HCO3 -交换。 。在从稀NaCl溶液中泵送Na + 和Cl -的动物中，Na + 或Cl -的摄取可能被选择性抑制，而伴随离子的通量保持不变。这被认为是Na + 和Cl -通量始终独立的补充证明。讨论了离子交换机制在内部介质中Na + 和Cl -水平的直接调节中的作用以及它们在酸调节中的关系基础平衡其他生理生态方面的考虑。

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