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Analyzing Source Sampling to Reduce Error in ECG Forward Simulations

机译:分析源采样以减少ECG前向仿​​真中的错误

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摘要

A continuing challenge in validating ECG Imaging is the persistent error in the associated forward problem observed in experimental studies. One possible cause of error is insufficient representation of the cardiac sources, which is often measured from only the ventricular epicardium, ignoring the endocardium and the atria. We hypothesize that measurements that completely cover the heart are required for accurate forward solutions. In this study, we used simulated and measured cardiac potentials to test the effect of different levels of sampling on the forward simulation. We found that omitting source samples on the atria increases the peak RMS error by a mean of 464 μV when compared the the fully sampled cardiac surface. Increasing the sampling on the atria in stages reduced the average error of the forward simulation proportionally to the number of additional samples and revealed some strategies may reduce error with fewer samples, such as adding samples to the AV plane and the atrial roof. Based on these results, we can design a sampling strategy to use in future validation studies.
机译:验证心电图成像的持续挑战是在实验研究中观察到的相关正向问题中的持续错误。错误的一种可能原因是心脏源的显示不充分,通常仅从心室心外膜测量而忽略心内膜和心房。我们假设精确的正向解决方案需要完全覆盖心脏的测量。在这项研究中,我们使用模拟和测量的心脏电势来测试不同采样水平对正向模拟的影响。我们发现,与完全采样的心脏表面相比,在心房上省略源样本会使峰值RMS误差平均增加464μV。分阶段增加对心房的采样会减少正向模拟的平均误差,而正向模拟的平均误差会与其他采样的数量成比例,并且揭示了一些策略可能会减少采样数量减少的误差,例如将采样添加到AV平面和心房顶。根据这些结果,我们可以设计一种抽样策略,以用于将来的验证研究。

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