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Preliminary Validity of the Modified Cigarette Evaluation Questionnaire in Predicting the Reinforcing Effects of Cigarettes that Vary in Nicotine Content

机译：改进型卷烟评估调查表在预测烟碱含量变化的卷烟的增强效果中的初步有效性

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Validity studies evaluating self-report measures in relation to behavioral preference of cigarettes varying in nicotine content are needed. The current study examined the relationship between ratings on the modified Cigarette Evaluation Questionnaire (mCEQ) and the relative reinforcing effects of Spectrum research cigarettes (15.8, 5.2, 2.4, 0.4 milligrams per gram of tobacco). Data for this secondary analysis were obtained from a double-blind study () evaluating the subjective and reinforcing effects of Spectrum cigarettes under acute smoking abstinence. Current smokers (N=26) were recruited from three vulnerable smoking populations (economically-disadvantaged women of reproductive age, opioid-maintained individuals, individuals with affective disorders). In Phase 1 (5 sessions), the mCEQ (Satisfaction, Psychological Reward, Enjoyment of Respiratory Tract Sensations, Craving Reduction, Aversion subscales) was administered following ad-lib smoking of Spectrum cigarettes and subscale differences scores were calculated by subtracting ratings of the 15.8 mg/g cigarette from ratings of the reduced nicotine content cigarettes. In Phase 2 (6 sessions), participants completed six two-dose concurrent choice tests. The relationship between mCEQ subscale difference scores from Phase 1 and nicotine dose choice from Phase 2 was examined using mixed-model repeated-measures analyses of variance. Higher Satisfaction and lower Aversion subscale difference scores were associated with choosing the 15.8 mg/g cigarette more than the 5.2, 2.4, and 0.4 mg/g cigarettes. Scores on the other mCEQ subscales were not associated with nicotine choice. These results provide support for validity of the mCEQ Satisfaction and Aversion subscales predicting the relative reinforcing effects and abuse liability of varying nicotine content cigarettes.
机译：需要进行有效性研究，以评估与尼古丁含量不同的卷烟的行为偏好相关的自我报告措施。当前的研究检查了改良型卷烟评估问卷（mCEQ）的等级与Spectrum研究卷烟的相对增强效果（每克烟草分别为15.8、5.2、2.4、0.4毫克）之间的关系。该次要分析的数据来自一项双盲研究（），该研究评估了光谱烟在急性戒烟下的主观和增强作用。当前的吸烟者（N = 26）是从三个脆弱的吸烟人群（经济上处于不利地位的育龄妇女，阿片类药物维持的个体，患有情感障碍的个体）招募的。在第1阶段（5节）中，随意吸烟光谱烟后施用mCEQ（满意度，心理奖励，享受呼吸道感觉，渴望减少，反感次级量表），并通过减去15.8的评分来计算次级量表差异得分。减少的尼古丁含量香烟的等级得出的毫克/克香烟。在第二阶段（6节）中，参与者完成了六个两剂同时选择测试。使用混合模型重复测量方差分析检查了第一阶段的mCEQ子量表差异评分与第二阶段的尼古丁剂量选择之间的关系。与选择5.2、2.4和0.4 mg / g的卷烟相比，选择15.8 mg / g的卷烟具有较高的满意度和较低的Aversion分量表差异评分。其他mCEQ子量表的得分与尼古丁选择无关。这些结果为mCEQ满意度和厌恶量表的有效性提供了支持，该量表预测了各种尼古丁含量香烟的相对增强作用和滥用责任。

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