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The REVAMP Trial to Evaluate HIV Resistance Testing in sub-Saharan Africa: A case study in clinical trial design in resource limited settings to optimize effectiveness and cost effectiveness estimates

机译：REVAMP试验以评估撒哈拉以南非洲地区的HIV抵抗力测试：在资源有限的环境中进行临床试验设计的案例研究以优化效果和成本效果估算

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BackgroundIn sub-Saharan Africa, rates of sustained HIV virologic suppression remain below international goals. HIV resistance testing, while common in resource-rich settings, has not gained traction due to concerns about cost and sustainability.

机译：背景在撒哈拉以南非洲，持续的HIV病毒学抑制率仍然低于国际目标。尽管在资源丰富的环境中普遍存在艾滋病毒抗药性测试，但由于对成本和可持续性的担忧而未能吸引人们的注意力。

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期刊名称 other
作者
Mark J. Siedner; Mwebesa B. Bwana; Yunus Moosa; Michelle Paul; Selvan Pillay; Suzanne McCluskey; Isaac Aturinda; Kevin Ard; Winnie Muyindike; Pravikrishnen Moodley; Jaysingh Brijkumar; Tamlyn Rautenberg; Gavin George; Brent Johnson; Rajesh T. Gandhi; Henry Sunpath; Vincent C. Marconi;
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年(卷),期 -1(18),4
年度 -1
页码 149–155
总页数 14
原文格式 PDF
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中图分类
关键词
HIV/AIDS sub-Saharan Africa antiretroviral therapy randomized controlled trial treatment failure cost-effectiveness genotypic resistance testing;

机译：艾滋病毒/艾滋病;撒哈拉以南非洲地区;抗逆转录病毒疗法;随机对照试验;治疗失败;成本效益;基因型耐药性检测;

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1. The REVAMP trial to evaluate HIV resistance testing in sub-Saharan Africa: a case study in clinical trial design in resource limited settings to optimize effectiveness and cost effectiveness estimates [J] . Siedner Mark J., Bwana Mwebesa B., Moosa Mahomed-Yunus S., HIV clinical trials . 2017,第4期

机译：评定试验评估亚撒哈拉非洲艾滋病毒电阻检测：资源有限环境中临床试验设计的案例研究，优化效率和成本效益估算
2. A pragmatic cluster randomised controlled trial to evaluate the safety, clinical effectiveness, cost effectiveness and satisfaction with point of care testing in a general practice setting – rationale, design and baseline characteristics [J] . Caroline Laurence, Angela Gialamas, Lisa Yelland, Trials . 2009,第1期

机译：一项实用的整群随机对照试验，用于评估在一般实践环境中的安全性，临床有效性，成本效益和对现场护理的满意程度–基本原理，设计和基线特征
3. A pragmatic cluster randomised controlled trial to evaluate the safety, clinical effectiveness, cost effectiveness and satisfaction with point of care testing in a general practice setting – rationale, design and baseline characteristics [J] . Caroline Laurence, Angela Gialamas, Lisa Yelland, Trials . 2008,第1期

机译：一项实用的整群随机对照试验，用于评估在一般实践环境中的安全性，临床有效性，成本效益和对现场护理的满意程度–基本原理，设计和基线特征
4. BENCH SCALE STUDIES TO EVALUATE THE EFFECTIVENESS OF SEVERAL BIOCIDES AND CHEMICALS WITH COMPARISONS TO FACTORY TRIALS [C] . Indrani S. Samaraweera, C. Gary Fischer, Diane L. Rheault, Sugar Processing Research Conference; 20020310-20020313; New Orleans,LA; US . 2002

机译：本量表研究，以评估几种杀生物剂和化学药品的功效，并与工厂试验进行比较
5. Cluster randomized intervention trial to evaluate the impact of the 'opt-out' versus 'opt-in' strategy on the uptake of HIV counseling and testing of tuberculosis patients in the Province of the Eastern Cape, South Africa. [D] . Pope, Diana Spies. 2007

机译：在南非东开普省进行的一项分组随机干预试验，评估了“选择退出”与“选择加入”策略对艾滋病毒咨询和结核病患者检测的接受程度。
6. A pragmatic cluster randomised controlled trial to evaluate the safety clinical effectiveness cost effectiveness and satisfaction with point of care testing in a general practice setting – rationale design and baseline characteristics [O] . Caroline Laurence, Angela Gialamas, Lisa Yelland, 2009

机译：一项实用的整群随机对照试验用于评估在一般实践环境中的安全性临床有效性成本效益和对现场护理的满意程度–基本原理设计和基线特征
7. Erratum to: A pragmatic cluster randomised controlled trial to evaluate the safety, clinical effectiveness, cost effectiveness and satisfaction with point of care testing in a general practice setting – rationale, design and baseline characteristics [O] . Caroline Laurence, null null, Angela Gialamas, 2012

机译：勘误至：一项实用的集群随机对照试验，用于评估在一般实践环境中的安全性，临床有效性，成本效益和对护理点测试的满意度–原理，设计和基线特征

The REVAMP Trial to Evaluate HIV Resistance Testing in sub-Saharan Africa: A case study in clinical trial design in resource limited settings to optimize effectiveness and cost effectiveness estimates

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