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Cerebrospinal Fluid Total Tau is Increased in Normal Pressure Hydrocephalus Patients who Undergo Successful Lumbar Drain Trials

机译：在成功进行腰椎引流试验的常压脑积水患者中脑脊液总Tau升高

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BackgroundIdiopathic normal pressure hydrocephalus (INPH) is a neurologic disease that affects <1% of those aged >65 years, but is difficult to distinguish from other diseases that present in this age group, such as Alzheimer’s disease. Large volume lumbar puncture and an external lumbar drain trial (ELD) are used to make a clinical diagnosis of INPH, but the accuracy of ELD is suspected.

机译：背景特发性常压性脑积水（INPH）是一种神经系统疾病，仅影响不到1％的65岁以上的老年人，但很难与该年龄段的其他疾病（例如阿尔茨海默氏病）区分开。大体积腰穿术和外部腰椎引流试验（ELD）用于进行INPH的临床诊断，但怀疑ELD的准确性。

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期刊名称 other
作者
Geoffrey Baird; Thomas J Montine; Jason J Chang; Shu-Ching Hu; Anthony M Avellino;
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作者单位

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年(卷),期 -1(9),5
年度 -1
页码 e1265
总页数 8
原文格式 PDF
正文语种
中图分类
关键词
cerebrospinal fluid normal pressure hydrocephalus tau protein lumbar drain;

机译：脑脊液;正常压力脑积水;tau蛋白;腰漏;

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专利

1. Cerebrospinal Fluid Total Tau is Increased in Normal Pressure Hydrocephalus Patients who Undergo Successful Lumbar Drain Trials [J] . Geoffrey Baird, Thomas J. Montine, Jason J. Chang, Cureus. . 2017,第5期

机译：在成功进行腰椎引流试验的常压脑积水患者中，脑脊液总Tau升高
2. Immunoreactivities of amyloid beta peptide((1-42)) and total tau protein in lumbar cerebrospinal fluid of patients with normal pressure hydrocephalus. [J] . Lins H, Wichart I, Bancher C, Journal of neural transmission . 2004,第3期

机译：正常压力脑积水患者腰椎脊髓液中β淀粉样蛋白（1-42）和总tau蛋白的免疫反应性
3. Cerebrospinal Fluid Amyloid-beta 42, Total Tau and Phosphorylated Tau are Low in Patients with Normal Pressure Hydrocephalus: Analogies and Differences with Alzheimer's Disease [J] . Santangelo Roberto, Cecchetti Giordano, Bernasconi Maria Paola, Journal of Alzheimer's disease: JAD . 2017,第1期

机译：脑脊液淀粉样蛋白β22，患者患者患者患者脑脊液淀粉样蛋白β22，患者患者较低：与阿尔茨海默病的类比和差异
4. A Fractional Pressure-Volume Model of Cerebrospinal Fluid Dynamics in Hydrocephalus [C] . Justin Kauffman, Corina S. Drapaca SEM Annual Conference Exposition on Experimental and Applied Mechanics . 2014

机译：脑脊液中脑脊液动力学的分数压力体积模型
5. Cerebrospinal fluid biomarkers for the differential diagnosis of normal pressure hydrocephalus and Alzheimer's disease [D] . Assuras, Stephanie 2010

机译：脑脊液生物标记物用于正常压力脑积水和阿尔茨海默氏病的鉴别诊断
6. Preoperative Phosphorylated Tau Concentration in the Cerebrospinal Fluid Can Predict Cognitive Function Three Years after Shunt Surgery in Patients with Idiopathic Normal Pressure Hydrocephalus [O] . Madoka Nakajima, Masakazu Miyajima, Ikuko Ogino, -1

机译：特发性常压性脑积水患者术前三年后脑脊液中磷酸化Tau浓度可预测认知功能
7. Preoperative Phosphorylated Tau Concentration in the Cerebrospinal Fluid Can Predict Cognitive Function Three Years after Shunt Surgery in Patients with Idiopathic Normal Pressure Hydrocephalus [O] . Madoka Nakajima, Masakazu Miyajima, Ikuko Ogino, 2018

机译：脑脊液中的术前磷酸化TAU浓度可以预测特发性正常压力脑积水患者分流手术后三年的认知功能

Cerebrospinal Fluid Total Tau is Increased in Normal Pressure Hydrocephalus Patients who Undergo Successful Lumbar Drain Trials

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