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首页> 美国卫生研究院文献>other >Cross-Country Individual Participant Analysis of 4.1 Million Singleton Births in 5 Countries with Very High Human Development Index Confirms Known Associations but Provides No Biologic Explanation for 2/3 of All Preterm Births
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Cross-Country Individual Participant Analysis of 4.1 Million Singleton Births in 5 Countries with Very High Human Development Index Confirms Known Associations but Provides No Biologic Explanation for 2/3 of All Preterm Births

机译：对人类发展指数非常高的5个国家的410万单身婴儿进行的跨国个人参与分析证实了已知的关联但没有生物学解释所有早产的2/3

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BackgroundPreterm birth is the most common single cause of perinatal and infant mortality, affecting 15 million infants worldwide each year with global rates increasing. Understanding of risk factors remains poor, and preventive interventions have only limited benefit. Large differences exist in preterm birth rates across high income countries. We hypothesized that understanding the basis for these wide variations could lead to interventions that reduce preterm birth incidence in countries with high rates. We thus sought to assess the contributions of known risk factors for both spontaneous and provider-initiated preterm birth in selected high income countries, estimating also the potential impact of successful interventions due to advances in research, policy and public health, or clinical practice.
机译：背景早产是围产期和婴儿死亡率的最常见单一原因，全球每年有1500万婴儿受到影响，全球死亡率也在上升。对危险因素的了解仍然很薄，预防性干预措施的收益有限。高收入国家的早产率存在很大差异。我们假设，了解这些广泛差异的基础可能导致采取干预措施，以降低高发国家的早产发生率。因此，我们寻求评估在选定的高收入国家中自发性和提供者性早产的已知危险因素的贡献，并评估由于研究，政策和公共卫生或临床实践的进步而成功进行干预的潜在影响。

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