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Flk1+ and VE-Cadherin+ Endothelial Cells Derived from iPSCs Recapitulates Vascular Development during Differentiation and Display Similar Angiogenic Potential as ESC-Derived Cells

机译：从iPSC衍生的Flk1 +和VE-钙黏着蛋白+内皮细胞概括了分化过程中的血管发育并显示了与ESC衍生细胞相似的血管生成潜能

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RationaleInduced pluripotent stem (iPS) cells have emerged as a source of potentially unlimited supply of autologous endothelial cells (ECs) for vascularization. However, the regenerative function of these cells relative to adult ECs and ECs derived from embryonic stem (ES) cells is unknown. The objective was to define the differentiation characteristics and vascularization potential of Fetal liver kinase (Flk)1⁺ and Vascular Endothelial (VE)-cadherin⁺ ECs derived identically from mouse (m)ES and miPS cells.

机译：基本原理诱导多能干（iPS）细胞已成为可能无限供应自体内皮细胞（EC）进行血管形成的来源。但是，这些细胞相对于成年EC和源自胚胎干（ES）细胞的EC的再生功能是未知的。目的是确定源自小鼠的胎肝激酶（Flk）1 ^{+ 和血管内皮（VE）-钙黏着蛋白^{+ EC的分化特征和血管形成潜力ES和miPS细胞。}}

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期刊名称 other
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Erin E. Kohler; Kishore K. Wary; Fei Li; Ishita Chatterjee; Norifumi Urao; Peter T. Toth; Masuko Ushio-Fukai; Jalees Rehman; Changwon Park; Asrar B. Malik;
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年(卷),期 -1(8),12
年度 -1
页码 e85549
总页数 13
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1. INTERACTIONS BETWEEN INDUCED PLURIPOTENT STEM CELL (IPSC)-DERIVED SMOOTH MUSCLE AND ENDOTHELIAL CELLS ENHANCE ANGIOGENIC GENE EXPRESSION IMPROVING VASCULAR REPAVING OF DECELLULARIZED RAT LUNG SCAFFOLDS [J] . Ho M. S., Chaudhary K., Stewart D. J. Cytotherapy . 2018,第5Suppla期

机译：诱导多能干细胞（IPSC）之间的相互作用（IPSC）的平滑肌和内皮细胞增强血管生成基因表达，提高脱叶大鼠肺支架的血管倒退
2. Anatomical response to anti-vascular endothelial growth factor (anti-VEGF) in patients with diabetic macular edema (DME) and its potential "in vitro" prediction by using Induced Pluripotent Stem Cell (IPSC)-derived endothelial cells (ECs) [J] . Lois Noemi, Margariti Andriana, Vila-Gonzalez Marta, Investigative ophthalmology & visual science . 2019,第9期

机译：患有诱导多能干细胞（IPSC）的患者患有糖尿病黄斑水肿（DME）患者抗血管内皮生长因子（抗VEGF）的解剖学响应及其“体外”预测（IPSC）的内皮细胞（ECS）
3. Endothelial and smooth muscle cells derived from human cardiac explants demonstrate angiogenic potential and suitable for design of cell-containing vascular grafts [J] . I. S. Zakharova, M. K. Zhiven, Sh. B. Saaya, Journal of Translational Medicine . 2017,第1期

机译：源自人心脏外植体的内皮细胞和平滑肌细胞具有血管生成潜力，适用于设计含细胞的血管移植物
4. Vascular Endothelial Growth Factor Induces Bone Marrow-Derived Mesenchymal Stem Cells Differentiation into Endothelial Cells [C] . Nan Wang, Rui Zhang, Shuijing Wang, International conference on applied biotechnology . 2014

机译：血管内皮生长因子诱导骨髓间充质干细胞分化为内皮细胞
5. Investigation of Developmental Cardiac Extracellular Matrix on Cardiac Fibroblasts (CF) Compaction and Induced Pluripotent Stem Cell Derived Cardiomyocytes (iPsc-Cms) Differentiation and Maturation [D] . Chen, Gina. 2020

机译：心肌成纤维细胞的发育心细胞外基质（CF）压实及诱导多能干细胞衍生心肌细胞（IPSC-CMS）分化和成熟的研究
6. Correction: Flk1+ and VE-Cadherin+ Endothelial Cells Derived from iPSCs Recapitulates Vascular Development during Differentiation and Display Similar Angiogenic Potential as ESC-Derived Cells [O] . Erin E. Kohler, Kishore K. Wary, Fei Li, -1

机译：校正：来自iPSC的Flk1 +和VE-钙黏着蛋白+内皮细胞在分化过程中概括了血管发育并显示了与ESC衍生细胞相似的血管生成潜能
7. Flk1+ and VE-cadherin+ endothelial cells derived from iPSCs recapitulates vascular development during differentiation and display similar angiogenic potential as ESC-derived cells. [O] . Erin E Kohler, Kishore K Wary, Fei Li, 2013

机译：源自ipsC的Flk1 +和VE-钙粘蛋白+内皮细胞在分化期间重现血管发育并显示与EsC衍生细胞相似的血管生成潜力。

Flk1+ and VE-Cadherin+ Endothelial Cells Derived from iPSCs Recapitulates Vascular Development during Differentiation and Display Similar Angiogenic Potential as ESC-Derived Cells

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