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Design Features of the Diabetes and Periodontal Therapy Trial (DPTT): A Multicenter Randomized Single-Masked Clinical Trial Testing the Effect of Non-surgical Periodontal Therapy on Glycosylated Hemoglobin (HbA1c) Levels in Subjects with Type 2 Diabetes and Chronic Periodontitis

机译:糖尿病和牙周治疗试验(DPTT)的设计特征:多中心随机单掩盖临床试验测试非手术性牙周治疗对2型糖尿病和慢性牙周炎患者糖化血红蛋白(HbA1c)水平的影响

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摘要

BackgroundEvidence suggests that periodontitis is associated with prevalent and incident type 2 diabetes mellitus (T2DM), raising the question of whether periodontitis treatment may improve glycemic control in patients with T2DM. Meta-analyses of mostly small clinical trials suggest that periodontitis treatment results in a modest reduction in glycosylated hemoglobin (Hb) A1c.
机译:背景证据表明,牙周炎与2型糖尿病(T2DM)的患病率和发病率有关,这引发了一个问题,即牙周炎治疗是否可以改善T2DM患者的血糖控制。大多数小型临床试验的荟萃分析表明,牙周炎治疗可导致糖基化血红蛋白(Hb)A1c适度降低。

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