首页> 美国卫生研究院文献>other >Drug Delivery Interfaces in the 21st Century: From Science Fiction Ideas to Viable Technologies
【2h】

Drug Delivery Interfaces in the 21st Century: From Science Fiction Ideas to Viable Technologies

机译:21世纪的药物输送界面:从科幻小说构想到可行技术

代理获取
本网站仅为用户提供外文OA文献查询和代理获取服务,本网站没有原文。下单后我们将采用程序或人工为您竭诚获取高质量的原文,但由于OA文献来源多样且变更频繁,仍可能出现获取不到、文献不完整或与标题不符等情况,如果获取不到我们将提供退款服务。请知悉。

摘要

Early science fiction envisioned the future of drug delivery as targeted micron-scale submarines and ‘Cyborg’ body parts. Here we describe the progression of the field toward technologies that are now beginning to capture aspects of this early vision. Specifically, we focus on the two most prominent types of systems in drug delivery – the intravascular microano drug carriers for delivery to the site of pathology and drug-loaded implantable devices that facilitate release with the pre-defined kinetics or in response to a specific cue. We discuss the unmet clinical needs that inspire these designs, the physiological factors that pose difficult challenges for their realization, and viable technologies that promise robust solutions. We also offer a perspective on where drug delivery may be in the next 50 years based on expected advances in material engineering and in the context of future diagnostics.
机译:早期的科幻小说将药物输送的目标定位为微米级潜艇和“ Cyborg”身体部位。在这里,我们描述了该领域向技术发展的进展,这些技术现在已经开始抓住这一早期愿景的各个方面。具体来说,我们专注于药物输送中两种最突出的系统类型–可以将其输送到病理部位的血管内微/纳米药物载体,以及可以按预先定义的动力学释放或响应药物释放的载有药物的可植入设备。具体提示。我们讨论了激发这些设计的未满足的临床需求,对其实现提出挑战的生理因素,以及有望提供可靠解决方案的可行技术。我们还将根据材料工程的预期进展以及未来的诊断方法,对未来50年内的药物输送前景提供一个观点。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
代理获取

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号