首页> 美国卫生研究院文献>AAPS PharmSciTech >A New Rapid On-Line Imaging Method to Determine Particle Size Distribution of Granules
【2h】

A New Rapid On-Line Imaging Method to Determine Particle Size Distribution of Granules

机译:确定颗粒粒径分布的新型快速在线成像方法

代理获取
本网站仅为用户提供外文OA文献查询和代理获取服务,本网站没有原文。下单后我们将采用程序或人工为您竭诚获取高质量的原文,但由于OA文献来源多样且变更频繁,仍可能出现获取不到、文献不完整或与标题不符等情况,如果获取不到我们将提供退款服务。请知悉。

摘要

The purpose of this research was to study the feasibility of the new image analysis method in the particle size determination of the granules. The method is capable of forming a three-dimensional topographic image of a sample surface from a digital picture. In the method, a flat granule bed surface was illuminated from three different directions, using the three primary colors (red, green, and blue). One color picture was taken by a digital camera, after which a topographic image of the object surface was constructed. The particle size distribution was then calculated from the image data. The particle size analysis method was tested both off-line and on-line. Off-line particle size measurement results determined by the image analysis method corresponded quite well to those of sieve analysis in the size fraction range 250–1,000 μm. In on-line application, images were successfully retrieved and median granule size trend could be calculated and followed during fluid bed granulations.
机译:这项研究的目的是研究新的图像分析方法在确定颗粒粒径方面的可行性。该方法能够从数字图片形成样本表面的三维地形图。在该方法中,使用三种原色(红色,绿色和蓝色)从三个不同的方向照亮了平坦的颗粒床表面。用数码相机拍摄一张彩色照片,然后构造物体表面的地形图。然后从图像数据计算粒度分布。离线和在线测试了粒度分析方法。通过图像分析方法确定的离线粒度测量结果与筛分分析的粒度分数范围在250–1,000μm的结果非常吻合。在在线应用中,成功获取了图像,并且可以计算出中值颗粒大小趋势,并在流化床制粒过程中进行跟踪。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
代理获取

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号