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Gamma-vinyl GABA increases nonvesicular release of GABA and glutamate in the nucleus accumbens in rats via action on anion channels and GABA transporters

机译：Gamma-乙烯基GABA通过对阴离子通道和GABA转运蛋白的作用增加大鼠核心腺中GABA和谷氨酸的谷氨酸释放

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摘要

Rationaleγ-Amino butyric acid (GABA) is a well-characterized inhibitory neurotransmitter in the central nervous system, which may also stimulate nonvesicular release of other neurotransmitters under certain conditions. We have recently reported that γ-vinyl GABA (GVG), an irreversible GABA transaminase inhibitor, elevates extracellular GABA but fails to alter dopamine release in the nucleus accumbens (NAc).

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期刊名称 other
作者
Xiao-Qing Peng; Eliot L. Gardner; Zheng-Xiong Xi;
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年(卷),期 -1(208),4
年度 -1
页码 511–519
总页数 15
原文格式 PDF
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关键词
γ-Vinyl GABA GABA Glutamate Anion channel GABA transporter Nucleus accumbens;

机译：γ-乙烯基GABA;GABA;谷氨酸盐;阴离子通道;GABA转运蛋白;伏隔核;

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专利

1. Gamma-vinyl GABA increases nonvesicular release of GABA and glutamate in the nucleus accumbens in rats via action on anion channels and GABA transporters [J] . PengX.-Q., GardnerE.L., XiZ.-X. Psychopharmacology . 2010,第4期

机译：γ-乙烯基GABA通过作用于阴离子通道和GABA转运蛋白增加大鼠伏隔核中GABA和谷氨酸的非囊泡释放
2. Gamma-vinyl GABA increases nonvesicular release of GABA and glutamate in the nucleus accumbens in rats via action on anion channels and GABA transporters. [J] . Peng XQ, Gardner EL, Xi ZX Psychopharmacology . 2010,第4期

机译：γ-乙烯基GABA通过作用于阴离子通道和GABA转运蛋白，增加了伏隔核中GABA和谷氨酸的非囊泡释放。
3. Gamma-vinyl GABA increases nonvesicular release of GABA and glutamate in the nucleus accumbens in rats via action on anion channels and GABA transporters [J] . Xiao-Qing Peng, Eliot L. Gardner, Zheng-Xiong Xi Psychopharmacology . 2010,第4期

机译：γ-乙烯基GABA通过作用于阴离子通道和GABA转运蛋白增加大鼠伏隔核中GABA和谷氨酸的非囊泡释放
4. Blockade of GABA Transporter (GAT-1) Modulates the GABAergic Transmission in the Rat Globus Pallidus [C] . Xiao-Tao Jin, Jean-Francois Pare, Yoland Smith Triennial Meeting of the International Basal Ganglia Society . 2009

机译：封锁GABA转运蛋白（GAT-1）调节大鼠Globus Pallidus中的加巴菌传播
5. Effect of extended access cocaine self-administration on GABA transmission in the nucleus accumbens. [D] . Purgianto, Anthony. 2015

机译：扩展访问可卡因自我给药对伏伏核中GABA传递的影响。
6. The Striatal Neurotensin Receptor Modulates Striatal and Pallidal Glutamate and GABA Release: Functional Evidence for a Pallidal Glutamate–GABA Interaction via the Pallidal–Subthalamic Nucleus Loop [O] . Luca Ferraro, Tiziana Antonelli, William T. O’Connor, 1998

机译：纹状体神经降压素受体调节纹状体和苍白质谷氨酸和GABA的释放：经由苍白质-丘脑底核环的谷氨酸-GABA相互作用的功能证据
7. The striatal neurotensin receptor modulates striatal and pallidal glutamate and GABA release: functional evidence for a pallidal glutamate–GABA interaction via the pallidal–subthalamic nucleus loop [O] . Ferraro, Luca, Antonelli, Tiziana, O'Connor, William T., 1998

机译：纹状体神经降压素受体调节纹状体和苍白质谷氨酸和GABA的释放：通过苍白质-丘脑底核环进行苍白质谷氨酸-GABA相互作用的功能证据
8. Inhibition of Transporter Mediated gamma-Aminobutyric Acid (GABA) Release by SKF 89976-A, a GABA Uptake Inhibitor, Studied in a Primary Neuronal Culture from Chicken. [R] . Lewin, L., Mattsson, M. O., Sellstroem, A. 1992

机译：通过sKF 89976-a释放转运蛋白介导的γ-氨基丁酸（GaBa）释放，sKF 89976-a是一种GaBa摄取抑制剂，在鸡的原代神经元培养物中进行研究。

Gamma-vinyl GABA increases nonvesicular release of GABA and glutamate in the nucleus accumbens in rats via action on anion channels and GABA transporters

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