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A Surface-Charge Study on Cellular-Uptake Behavior of F3-Peptide-Conjugated Iron Oxide Nanoparticles

机译：F3肽缀合氧化铁纳米粒子细胞摄取行为的表面电荷研究

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摘要

Surface-charge measurements of mammalian cells in terms of Zeta potential are demonstrated as a useful biological characteristic in identifying cellular interactions with specific nanomaterials. A theoretical model of the changes in Zeta potential of cells after incubation with nanoparticles is established to predict the possible patterns of Zeta-potential change to reveal the binding and internalization effects. The experimental results show a distinct pattern of Zeta potential change that allows the discrimination of human normal breast epithelial cells (MCF-10A) from human cancer breast epithelial cells (MCF-7) when the cells are incubated with dextran coated iron oxide nanoparticles that contain tumor-homing F3 peptides, where the tumor-homing F3 peptide specifically bound to nucleolin receptors that are overexpressed in cancer breast cells.

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期刊名称 other
作者
Yu Zhang; Mo Yang; Ji-Ho Park; Jennifer Singelyn; Huiqing Ma; Michael J. Sailor; Erkki Ruoslahti; Mihrimah Ozkan; Cengiz Ozkan;
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作者单位

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年(卷),期 -1(5),17
年度 -1
页码 1990–1996
总页数 15
原文格式 PDF
正文语种
中图分类
关键词
cellular uptake F3 peptide iron oxide nanoparticles Zeta potential;

机译：细胞摄取;F3肽;氧化铁纳米粒子;Zeta电位;

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专利

1. A Surface-Charge Study on Cellular-Uptake Behavior of F3-Peptide-Conjugated Iron Oxide Nanoparticles [J] . Zhang Y, Yang M, Park JH, Small . 2009,第17期

机译：F3肽共轭氧化铁纳米粒子的细胞摄取行为的表面电荷研究。
2. Viscoelastic and mechanical behaviors of magneto-rheological carbonyl iron/natural rubber composites with magnetic iron oxide nanoparticle [J] . Kwon Seung Hyuk, Lee Chul Joo, Choi Hyoung Jin, Smart Materials & Structures . 2019,第4期

机译：磁力氧化铁纳米粒子磁流变羰基钢/天然橡胶复合材料的粘弹性和力学行为
3. Oil Phase Evaporation-Induced Self-Assembly of Hydrophobic Nanoparticles into Spherical Clusters with Controlled Surface Chemistry in an Oil-in-Water Dispersion and Comparison of Behaviors of Individual and Clustered Iron Oxide Nanoparticles [J] . Penghe Qiu, Christina Jensen, Njoku Charity, Journal of the American Chemical Society . 2010,第50期

机译：在水包油分散液中油相蒸发诱导疏水性纳米粒子自组装成具有受控表面化学的球形簇，并且比较单个和簇状氧化铁纳米颗粒的行为
4. Magnetic field -dependent protein corona onto superparamagnetic iron oxide nanoparticles influences their biological behaviors [C] . Yue Zhu, Ziyao Liu, Fang Lan, Society for Biomaterials annual meeting and exposition . 2017

机译：超顺磁性氧化铁纳米粒子上的磁场依赖性蛋白电晕会影响其生物学行为
5. Observed super-spin glass behavior in nickel zinc iron oxide nanoparticles [D] . Adair, Antony 2009

机译：镍锌氧化铁纳米粒子中观察到的超旋转玻璃行为
6. Oil Phase Evaporation Induced Self-Assembly of Hydrophobic Nanoparticles into Spherical Clusters with Controlled Surface Chemistry in an Oil-in-Water Dispersion and Comparison of Behaviors of Individual and Clustered Iron Oxide Nanoparticles [O] . Penghe Qiu, Christina Jensen, Njoku Charity, -1

机译：疏水性纳米粒子的油相蒸发诱导自组装成球形集群与控制的表面化学在油中的水分散体个体和集群的氧化铁纳米颗粒性能对比
7. A surface-charge study on cellular-uptake behavior of F3-peptide-conjugated iron oxide nanoparticles [O] . Zhang, Y, Yang, M, Park, JH, 2009

机译：F3肽共轭氧化铁纳米颗粒的细胞摄取行为的表面电荷研究

A Surface-Charge Study on Cellular-Uptake Behavior of F3-Peptide-Conjugated Iron Oxide Nanoparticles

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