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Factors associated with serum retinol alpha-tocopherol carotenoids and selenium in Hispanics with problems of HIV chronic hepatitis C and drug use

机译：与艾滋病毒慢性丙型肝炎和药物使用问题与血清视黄醇α-生育酚类胡萝卜素和硒相关的因素

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摘要

The effects of hepatitis and drug use on nutritional problems in HIV infection have rarely been examined despite the importance of drug use in the global HIV pandemic. We examined the effects of HIV, hepatitis C and drug use on serum micronutrients in 300 USA Hispanic adults. Chronic hepatitis C infection was associated with lower serum retinol (−8.2 ug/dl, p<0.0001), alpha-tocopherol (−0.10 ln ug/dl, p=0.024), and carotenoids (−19.8 ug/dl, p<0.0001). HIV infection was associated with lower selenium (−6.1 ug/l, p=0.028). Elevated trigycerides in HIV infection were associated with higher serum retinol and alpha-tocopherol. Drug use was not independently associated with micronutrient alterations. We conclude that hepatitis C is an important determinant of low serum micronutrients, and should be considered in any nutritional assessment of HIV infected populations. Since the safety of micronutrient supplementation is not established, policy for appropriate HIV clinical care should distinguish between populations with and without hepatitis co-infection.

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  • 期刊名称 other
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  • 作者单位
  • 年(卷),期 -1(30),3
  • 年度 -1
  • 页码 285–299
  • 总页数 11
  • 原文格式 PDF
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  • 关键词

    HIV drug use hepatitis C serum micronutrients;

    机译：艾滋病毒;毒品使用;丙型肝炎;血清微量营养素;

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