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Drinking Typography Established by Scheduled Induction Predicts Chronic Heavy Drinking in a Monkey Model of Ethanol Self-Administration

机译：通过计划归纳法建立的饮酒排版预测在乙醇自我管理的猴子模型中的长期大量饮酒。

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BackgroundWe have developed an animal model of alcohol self-administration that initially employs schedule-induced polydipsia (SIP) to establish reliable ethanol consumption under open access (22 h/d) conditions with food and water concurrently available. SIP is an adjunctive behavior that is generated by constraining access to an important commodity (e.g., flavored food). The induction schedule and ethanol polydipsia generated under these conditions affords the opportunity to investigate the development of drinking typologies that lead to chronic, excessive alcohol consumption.

机译：背景我们开发了一种酒精自我管理的动物模型，该模型最初采用进度诱导的多饮（SIP）在开放获取（22 h / d）的条件下建立可靠的乙醇消耗，同时提供食物和水。 SIP是通过限制对重要商品（例如调味食品）的访问而产生的辅助行为。在这些条件下产生的诱导时间表和乙醇多饮症提供了研究导致长期过度饮酒的饮酒类型发展的机会。

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期刊名称 other
作者
Kathleen A. Grant; Xiaoyan Leng; Heather L. Green; Kendall T. Szeliga; Laura S. M. Rogers; Steven W. Gonzales;
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作者单位

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年(卷),期 -1(32),10
年度 -1
页码 1824–1838
总页数 30
原文格式 PDF
正文语种
中图分类
关键词
Monkeys Self-Administration Ethanol Schedule-Induced Polydipsia Animal Models;

机译：猴子;自我管理;乙醇;日程诱发的多饮症;动物模型;

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专利

1. Drinking typography established by scheduled induction predicts chronic heavy drinking in a monkey model of ethanol self-administration. [J] . Grant KA, Leng X, Green HL, Alcoholism: Clinical and experimental research . 2008,第10期

机译：通过计划的诱导建立的饮酒印刷术可以预测在乙醇自我给药的猴子模型中的长期大量饮酒。
2. Failure of a schedule-induction procedure to increase ethanol intake in an established limited-access self-administration condition. [J] . Samson HH, Chappell A Alcohol . 2003,第3期

机译：在建立的有限访问自我管理条件下，按时间表进行诱导程序无法增加乙醇摄入量。
3. Diurnal variation in plasma ethanol levels of TO and CBA mice on chronic ethanol drinking or ethanol liquid diet schedules. [J] . Jelic P, Shih MF, Taberner PV Psychopharmacology . 1998,第2期

机译：在长期饮酒或无糖饮食中，TO和CBA小鼠血浆乙醇水平的昼夜变化。
4. INDUCTION OF MAMMALIAN CELL CHRONIC CYTOTOXICITY AND ACUTE GENOMIC DNA DAMAGE BY DRINKING WATER DISINFECTION BYPRODUCTS [C] . Michael J. Plewa, Mark G. Muellner, Susan D. Richardson American Chemical Society Division of Environmental Chemistry Symposium . 2008

机译：通过饮用水消毒副产品诱导哺乳动物细胞慢性细胞毒性和急性基因组DNA损伤
5. The effects of chronic ethanol self-administration on the serotonin system in monkeys [D] . Burnett, Elizabeth J. 2012

机译：慢性乙醇自我给药对猴子血清素系统的影响
6. Chronic Drinking During Adolescence Predisposes the Adult Rat for Continued Heavy Drinking: Neurotrophin and Behavioral Adaptation after Long-Term Continuous Ethanol Exposure [O] . Gina M. Fernandez, William N. Stewart, Lisa M. Savage -1

机译：青春期期间的长期饮酒使成年大鼠继续大量饮酒：长期连续暴露于乙醇后的神经营养蛋白和行为适应
7. Drinking Typography Established by Scheduled Induction Predicts Chronic Heavy Drinking in a Monkey Model of Ethanol Self-Administration [O] . Kathleen A. Grant, Xiaoyan Leng, Heather L. Green, 2008

机译：预定诱导建立的饮酒印刷术预测乙醇自我管理猴子模型中的慢性重饮用

Drinking Typography Established by Scheduled Induction Predicts Chronic Heavy Drinking in a Monkey Model of Ethanol Self-Administration

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