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Hybrid photodetector for single-molecule spectroscopy and microscopy

机译:用于单分子光谱和显微镜的混合光电探测器

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摘要

We report benchmark tests of a new single-photon counting detector based on a GaAsP photocathode and an electron-bombarded avalanche photodiode developed by Hamamatsu Photonics. We compare its performance with those of standard Geiger-mode avalanche photodiodes. We show its advantages for FCS due to the absence of after-pulsing and for fluorescence lifetime measurements due to its excellent time resolution. Its large sensitive area also greatly simplifies setup alignment. Its spectral sensitivity being similar to that of recently introduced CMOS SPADs, this new detector could become a valuable tool for single-molecule fluorescence measurements, as well as for many other applications.
机译:我们报告了基于GaAsP光电阴极和Hamamatsu Photonics开发的电子轰击雪崩光电二极管的新型单光子计数检测器的基准测试。我们将其性能与标准盖革模式雪崩光电二极管的性能进行比较。由于没有后脉冲,我们展示了其对FCS的优势,并由于其出色的时间分辨率而为荧光寿命测量提供了优势。其较大的敏感区域也大大简化了设置对准。它的光谱灵敏度与最近推出的CMOS SPAD相似,这种新型检测器可能成为单分子荧光测量以及许多其他应用的有价值的工具。

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