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Crosstalk at the initial encounter: Interplay between host defense and ameba survival strategies

机译:最初的相遇:主机防御与ameba生存策略之间的相互作用

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摘要

The host-parasite relationship is based on a series of interplays between host defense mechanisms and parasite survival strategies. Progress has been made in understanding the role of host immune response in amebiasis. While host cells elaborate diverse mechanisms for pathogen expulsion, amebae have also developed complex strategies to modulate host immune response and facilitate their own survival. This paper will give an overview of current research on the mutual interactions between host and Entamoeba histolytica in human and experimental amebiasis. Understanding this crosstalk is crucial for the effective design and implementation of new vaccines and drugs for this leading parasitic disease.
机译:宿主-寄生虫的关系是基于宿主防御机制和寄生虫生存策略之间的一系列相互作用。在了解宿主免疫反应在阿米巴病中的作用方面已取得进展。尽管宿主细胞阐明了多种驱除病原体的机制,但变形虫还开发了复杂的策略来调节宿主的免疫反应并促进其自身存活。本文将概述目前在人类和实验性阿米巴病中宿主与溶组织变形杆菌之间的相互作用的最新研究。了解这种串扰对于有效设计和实施针对这种主要寄生虫病的新疫苗和药物至关重要。

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