• 主题
高级搜索  >
历史搜索 清空历史
首页> 美国卫生研究院文献>other >Cimicifuga species identification by high performance liquid chromatography-photodiode array/mass spectrometric/evaporative light scattering detection for quality control of black cohosh products
【2h】

Cimicifuga species identification by high performance liquid chromatography-photodiode array/mass spectrometric/evaporative light scattering detection for quality control of black cohosh products

机译：高效液相色谱-光电二极管阵列/质谱/蒸发光散射检测法鉴定黑升麻产品的黑升麻产品质量

代理获取
本网站仅为用户提供外文OA文献查询和代理获取服务，本网站没有原文。下单后我们将采用程序或人工为您竭诚获取高质量的原文，但由于OA文献来源多样且变更频繁，仍可能出现获取不到、文献不完整或与标题不符等情况，如果获取不到我们将提供退款服务。请知悉。
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Black cohosh has become one of the most important herbal products in the U.S. dietary supplements market. It is manufactured from roots and rhizomes of Cimicifuga racemosa (Ranunculaceae). Botanical identification of the raw starting material is a key step in the quality control of black cohosh preparations. The present report summarizes a fingerprinting approach based on HPLC-PDA/MS/ELSD that has been developed and validated using a total of ten Cimicifuga species. These include three North American species, C. racemosa, C. americana, C. rubifolia, and seven Asian species, C. acerina, C. biternat, C. dahurica, C. heracleifolia, C. japonica, C. foetida, and C. simplex. The chemotaxonomic distinctiveness of the HPLC fingerprints allows identification of all ten Cimicifuga species. The triterpene glycosides cimigenol-3-O-arabinoside (>3), cimifugin (>12), and cimifugin-3-O-glucoside (>18) were determined to be suitable species-specific markers for the distinction of C. racemosa from the other Cimicifuga species. In addition to identification, the fingerprint method provided insight into chemical interconversion processes occurring between the diverse triterpene glycosides contained in black cohosh. The reported method has proven its usefulness in the botanical standardization and quality control of black cohosh products.
机译：黑升麻已经成为美国膳食补充剂市场上最重要的草药产品之一。它由Cimimicugauga racemosa（毛an科）的根和根茎制成。原料原料的植物学鉴定是黑升麻制剂质量控制中的关键步骤。本报告总结了一种基于HPLC-PDA / MS / ELSD的指纹方法，该方法已使用总共十种Cimicifuga物种进行了开发和验证。这些物种包括三个北美种，C。racemosa，C。americana，C。rubifolia和七个亚洲种，C。acerina，C。biternat，C。dahurica，C。heracleifolia，C。japonica，C。foetida和C.单面HPLC指纹图谱的化学分类学独特性可用于鉴定所有十种升麻。三萜糖苷cimigenol-3-O-阿拉伯糖苷（> 3 ），cimifugin（> 12 ）和cimifugin-3-O-葡萄糖苷（> 18 ）被确定为合适的物种特异性标记，用于将消旋梭状芽孢杆菌与其他Cimicifuga物种区分开。除了鉴定外，指纹方法还提供了对黑升麻中所含的不同三萜糖苷之间发生化学互变过程的深入了解。已报道的方法已证明其在黑升麻产品的植物标准化和质量控制中的有用性。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
代理获取

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号