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Exposure to secondhand tobacco smoke is associated with reduced muscle strength in US adults

机译:暴露于二手烟会导致美国成年人的肌肉力量下降

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摘要

Secondhand tobacco smoke (SHS) exposure is a well-established risk factor for several diseases in adults. Despite the evidence that active tobacco smoke is harmful for the muscles, the association between SHS and muscle strength is still uncertain.We analyzed data from 5390 nonsmoking U.S. adults aged >30 years who participated in the National Health and Nutrition Examination Survey (NHANES) 2011-2014. Exposure to SHS was assessed with serum cotinine concentrations. Grip strength was measured using a Takei digital handgrip dynamometer, and combined grip strength was calculated as the sum of the largest reading from each hand. Median (interquartile range) serum cotinine and grip strength were 0.015 ng/mL (IQR 0.011-0.36) and 65.5 kg (IQR 53.4-86.4), respectively. After adjusting for sociodemographic, anthropometric, health-related behavioral, and clinical risk factors, the highest (0.047-9.9 ng/mL) vs lowest (≤0.011 ng/mL) quartile of serum cotinine was associated with a reduction in combined grip strength of 1.41 kg (95%CI: -2.58, -0.24), p-trend=0.02. These results were consistent across socio-demographic and clinical subgroups. In the US nonsmoking adult population, even low levels of exposure to passive smoking were associated with decreased grip strength. Despite great achievements in tobacco control, extending public health interventions to reduce SHS exposure is still needed.
机译:二手烟暴露是成年人几种疾病的公认危险因素。尽管有证据表明活跃的烟草烟雾对肌肉有害,但SHS和肌肉力量之间的关系仍不确定。我们分析了5390名30岁以上的美国吸烟成年人的数据,这些成年人参加了2011年美国国家健康与营养检查(NHANES) -2014。用血清可替宁浓度评估SHS暴露。使用Takei数字式握力测力计测量握力,并计算组合握力为每只手最大读数的总和。血清可替宁的中位数(四分位数间距)和抓地力分别为0.015 ng / mL(IQR 0.011-0.36)和65.5 kg(IQR 53.4-86.4)。在调整了社会人口统计学,人体测量学,健康相关的行为和临床危险因素后,血清可替宁的最高四分位数(0.047-9.9 ng / mL)与最低四分位数(≤0.011ng / mL)与降低的综合握力有关。 1.41千克(95%CI:-2.58,-0.24),p-趋势= 0.02。这些结果在社会人口统计学和临床​​亚组之间是一致的。在美国的非吸烟成年人口中,即使是低水平的被动吸烟也与握力下降有关。尽管在烟草控制方面取得了巨大成就,但仍需要扩大公共卫生干预措施以减少SHS暴露。

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