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Correction propagation for user-assisted optical coherence tomography segmentation: general framework and application to Bruch’s membrane segmentation

机译:用户辅助光学相干断层扫描分割的校正传播:通用框架及其在Bruch膜分割中的应用

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摘要

Optical coherence tomography (OCT) is a commonly used ophthalmic imaging modality. While OCT has traditionally been viewed cross-sectionally (i.e., as a sequence of B-scans), higher A-scan rates have increased interest in OCT visualization and analysis. The recent clinical introduction of OCT angiography (OCTA) has further spurred this interest, with chorioretinal OCTA being predominantly displayed via projections. Although visualization and quantitation are natural for many retinal features (e.g., drusen and vasculature), it requires segmentation. Because manual segmentation of volumetric OCT data is prohibitively laborious in many settings, there has been significant research and commercial interest in developing automatic segmentation algorithms. While these algorithms have achieved impressive results, the variability of image qualities and the variety of ocular pathologies cause even the most robust automatic segmentation algorithms to err. In this study, we develop a user-assisted segmentation approach, complementary to fully-automatic methods, wherein correction propagation is used to reduce the burden of manually correcting automatic segmentations. The approach is evaluated for Bruch’s membrane segmentation in eyes with advanced age-related macular degeneration.
机译:光学相干断层扫描(OCT)是一种常用的眼科成像设备。尽管传统上将OCT视为横截面图(即,作为B扫描序列),但较高的A扫描速率已引起对OCT可视化和分析的兴趣。 OCT血管造影(OCTA)的最新临床应用进一步激发了这种兴趣,脉络膜视网膜OCTA主要通过投影显示。尽管可视化和定量对于许多视网膜特征(例如玻璃疣和脉管系统)来说是自然的,但仍需要进行分割。由于在许多情况下手动分割体积OCT数据非常费力,因此开发自动分割算法引起了广泛的研究和商业兴趣。尽管这些算法取得了令人印象深刻的结果,但图像质量的变化和眼部病理的变化甚至导致最强大的自动分割算法也出错了。在这项研究中,我们开发了一种用户辅助的分割方法,作为全自动方法的补充,其中校正传播用于减少手动校正自动分割的负担。对这种方法进行了评估,以评估与年龄相关的老年性黄斑变性的眼睛中布鲁赫膜的分割情况。

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