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Recent population genomic insights into the genetic basis of arsenic tolerance in humans: the difficulties of identifying positively selected loci in strongly bottlenecked populations

机译：人类砷耐受性遗传基础的最新人群基因组学见识：在瓶颈严重的人群中确定阳性选择基因座的困难

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摘要

Map of endemic areas with high arsenic levels in natural water sources around the globe (Arriaza et al. ), with regions indicated on the red-scale frequently having significant public health issues associated with exposure. The regions denoted in green boxes have evidence of increased tolerance, perhaps owing to long-term exposure, and thus the local populations are fruitful examples in which to study the evolutionary response to arsenic

机译：全球自然水源中砷含量高的地方流行区地图（Arriaza等人），红色标度的地区经常存在与接触有关的重大公共卫生问题。绿框表示的区域可能是由于长期暴露而导致耐受性增强的证据，因此，当地居民是研究砷对砷的进化反应的有效实例。

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期刊名称 Heredity
作者
Mario Apata; Susanne P. Pfeifer;
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年(卷),期 2020(124),2
年度 2020
页码 -1
总页数 10
原文格式 PDF
正文语种
中图分类遗传学;进化论、生物系统发育;
关键词
Population genetics; Evolutionary genetics;

机译：人口遗传学;进化遗传学;

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专利

1. Recent population genomic insights into the genetic basis of arsenic tolerance in humans: the difficulties of identifying positively selected loci in strongly bottlenecked populations [J] . Heredity: An International Journal of Genetics . 2020,第2期

机译：最近的人口基因组洞察人类砷耐受性的遗传基础：在强瓶颈中识别正面选择的群体的困难
2. A comparison of the variability spectra of two genomic loci in a European group of individuals reveals fundamental differences pointing to selection or a population bottleneck. [J] . Schmegner C, Hoegel J, Vogel W, Annals of Human Genetics . 2007,第Pta3期

机译：欧洲一组个人中两个基因组基因座变异性谱的比较揭示了指向选择或种群瓶颈的根本差异。
3. Trans-ethnic fine-mapping of genetic loci for body mass index in the diverse ancestral populations of the Population Architecture using Genomics and Epidemiology (PAGE) Study reveals evidence for multiple signals at established loci [J] . Fernandez-Rhodes Lindsay, Gong Jian, Haessler Jeffrey, Human Genetics . 2017,第6期

机译：使用基因组学和流行病学的人口架构中不同祖先群体的体重指数遗传基因群的跨族 - 群体细制
4. Population genetic data of 21 autosomal loci in Guangdong Han Population [C] . LI Shuang Lin, LIU Chao, LIU Hong, International Conference on Advanced Engineering Materials and Architecture Science . 2013

机译：广东汉族21例常染色体基因座的群体遗传数据
5. Genomic mapping of leaf rust and stem rust resistance loci in durum wheat and use of RAD-Genotype by Sequencing for the study of population genetics in Puccinia triticina [D] . Aoun, Meriem. 2016

机译：杜兰姆小麦叶片锈病和茎锈抗性基因座的基因组映射及吡锡群群体遗传学研究的用途抗基因型
6. Population Bottlenecks and Nonequilibrium Models in Population Genetics. III. Genic Homozygosity in Populations Which Experience Periodic Bottlenecks [O] . Takeo Maruyama, Paul A. Fuerst 1985

机译：人口遗传学中的人口瓶颈和非平衡模型。三经历周期性瓶颈的人群中的纯合子纯合性
7. Recent population genomic insights into the genetic basis of arsenic tolerance in humans: the difficulties of identifying positively selected loci in strongly bottlenecked populations [O] . Mario Apata, Susanne P. Pfeifer 2019

机译：最近的人口基因组洞察人类砷耐受性的遗传基础：在强瓶颈中识别正面选择基因座的困难

Recent population genomic insights into the genetic basis of arsenic tolerance in humans: the difficulties of identifying positively selected loci in strongly bottlenecked populations

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