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首页> 美国卫生研究院文献>International Journal of Environmental Research and Public Health >Cancer Mortality and Deprivation in the Proximity of Polluting Industrial Facilities in an Industrial Region of Spain
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Cancer Mortality and Deprivation in the Proximity of Polluting Industrial Facilities in an Industrial Region of Spain

机译：西班牙工业区附近污染严重的工业设施导致的癌症死亡率和剥夺

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Residential proximity to industrial facilities that release pollutants is a source of exposure to a high number of toxics, many of them known or suspected carcinogens. The objective of the study was to analyze the association between lung, larynx, bladder, and kidney cancer mortality and deprivation in areas proximate to polluting industrial facilities in Cadiz, a highly industrialized province in Spain. An ecological study at census tract level was carried out to estimate the mortality rates associated with deprivation and proximity to polluting industrial facilities (1–5 km) using the Besag–York–Mollié model. The results show a negative social gradient for lung and larynx cancers in males and greater risk of lung cancer was observed in the least deprived areas in females. These associations were found regardless the distance to industrial facilities. Increasing excess risk (relative risk; 95% credibility interval) of lung cancer for males (1.09; 1.02–1.16 at 5 km vs 1.24; 1.08–1.41 at 1 km) and bladder cancer for males (1.11; 1.01–1.22 at 5 km vs 1.32; 1.08–1.60 at 1 km) and females (1.32; 1.04–1.69 at 4 km vs 1.91; 1.28–2.86 at 1 km) was found as proximity to polluting industrial facilities increased. For kidney cancer, high risks were observed near such facilities for both sexes. Knowing the possible influence of industrial pollution and social inequalities over cancer risk allows the definition of policies aimed at reducing the risk.
机译：居民区靠近释放污染物的工业设施，是暴露于多种有毒物质的来源，其中许多是已知或可疑的致癌物。这项研究的目的是分析西班牙高度工业化的加的斯市工业设施附近污染地区的肺癌，喉癌，膀胱癌和肾癌死亡率与剥夺之间的关系。使用Besag-York-Mollié模型进行了人口普查区域的生态研究，以估计与贫困和接近污染性工业设施（1-5公里）相关的死亡率。结果表明，男性肺癌和喉癌的社会梯度为负，在女性最贫困的地区，患肺癌的风险更高。无论与工业设施的距离如何，都发现了这些关联。男性的肺癌（1.09; 5 km时1.02–1.16 vs 1.24; 1.08–1.41 1km时）的男性过高风险（相对风险; 95％可信区间）vs男性的膀胱癌（5 km时1.11; 1.01–1.22） vs. 1.32；在1 km处为1.08–1.60）和女性（1.32；在4 km处为1.04–1.69，而在1. km处为1.91；在1 km处为1.28–2.86）是因为靠近污染性工业设施的程度增加。对于肾癌，在这样的设施附近，男女双方都观察到高风险。知道工业污染和社会不平等对癌症风险的可能影响，就可以定义旨在降低风险的政策。

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