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Mechanisms of Bioactive Glass on Caries Management: A Review

机译：生物活性玻璃对龋齿管理的作用机理研究进展

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摘要

This review investigates the mechanisms of bioactive glass on the management of dental caries. Four databases (PubMed, Web of Science, EMBASE (via Ovid), Medline (via Ovid)) were systematically searched using broad keywords and terms to identify the literature pertaining to the management of dental caries using “bioactive glass”. Titles and abstracts were scrutinized to determine the need for full-text screening. Data were extracted from the included articles regarding the mechanisms of bioactive glass on dental caries management, including the aspect of remineralizing effect on enamel and dentine caries, and antimicrobial effect on cariogenic bacteria. After removal of duplicates, 1992 articles were identified for screening of the titles and abstracts. The full texts of 49 publications were scrutinized and 23 were finally included in this review. Four articles focused on the antimicrobial effect of bioactive glass. Twelve papers discussed the effect of bioactive glass on demineralized enamel, while 9 articles investigated the effect of bioactive glass on demineralized dentine. In conclusion, bioactive glass can remineralize caries and form apatite on the surface of enamel and dentine. In addition, bioactive glass has an antibacterial effect on cariogenic bacteria of which may help to prevent and arrest dental caries.
机译：这项审查调查生物活性玻璃对龋齿管理的机制。使用广泛的关键词和术语系统搜索了四个数据库（PubMed，Web of Science，EMBASE（通过Ovid），Medline（通过Ovid）），以识别与使用“生物活性玻璃”治疗龋齿有关的文献。仔细检查标题和摘要，以确定是否需要全文筛选。从包括在内的文章中提取了有关生物活性玻璃对龋齿治疗机制的数据，包括对牙釉质和牙本质龋齿的再矿化作用以及对龋齿细菌的抗菌作用方面。删除重复项后，确定了1992篇文章用于标题和摘要的筛选。审查了49个出版物的全文，并最终将23个出版物纳入了本文。有四篇文章关注于生物活性玻璃的抗菌作用。 12篇论文讨论了生物活性玻璃对脱矿质牙釉质的影响，而9篇文章研究了生物活性玻璃对脱矿质牙本质的影响。总之，生物活性玻璃可以使龋齿再矿化，并在牙釉质和牙本质表面形成磷灰石。此外，生物活性玻璃对龋齿细菌具有抗菌作用，可以帮助预防和阻止龋齿。

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