LncRNAs join hands together to regulate neuroblastoma progression

机译：LncRNA携手调节神经母细胞瘤的进展

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Trait associated single nucleotide polymorphisms often overlap with noncoding transcripts but their contribution to disease phenotype is poorly investigated. Our study on neuroblastoma risk associated 6p22.3 locus derived long noncoding RNAs (lncRNAs) demonstrates that functional co-operation between sense-antisense and lncRNAs control neuroblastoma progression via regulating regulatory axis.

机译：特质相关的单核苷酸多态性经常与非编码转录本重叠，但是对疾病表型的贡献却很少被研究。我们对神经母细胞瘤风险相关的6p22.3基因座衍生的长非编码RNA（lncRNA）的研究表明，有义反义和lncRNA之间的功能性合作通过调节调节轴来控制神经母细胞瘤的进展。

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期刊名称 Molecular Cellular Oncology
作者
Tanmoy Mondal; Chandrasekhar Kanduri;
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作者单位

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年(卷),期 2019(6),1
年度 2019
页码 -1
总页数 3
原文格式 PDF
正文语种
中图分类肿瘤学;
关键词
GWAS SNPs; lncRNA; neuroblastoma; SOX9; USP36;

机译：GWAS SNPs;lncRNA;神经母细胞瘤;SOX9;USP36;

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专利

1. LncRNA RMRP silence curbs neonatal neuroblastoma progression by regulating microRNA-206/tachykinin-1 receptor axis via inactivating extracellular signal-regulated kinases [J] . Pan Juntao, Zhang Da, Zhang Jiao, Cancer biology & therapy . 2019,第4a6期

机译：LNCRNA RMRP沉默通过灭活细胞外信号调节激酶来调节MicroRNA-206 / Tachykinin-1受体轴来静置新生儿神经母细胞瘤进展
2. Pan-cancer analysis reveals TAp63-regulated oncogenic lncRNAs that promote cancer progression through AKT activation [J] . Marco Napoli, Xiaobo Li, Hayley D. Ackerman, Nature Communications . 2020,第1期

机译：泛癌分析揭示了Tap63调节的致癌LNCRNA通过AKT激活促进癌症进展
3. LncRNA DLX6-AS1 Promotes the Progression of Neuroblastoma by Activating STAT2 via Targeting miR-506-3p [J] . Yanping Hu, Huifang Sun, Jiting Hu, Cancer Management and Research . 2020,第4期

机译：LNCRNA DLX6-AS1通过靶向MIR-506-3P激活STAT2来促进神经母细胞瘤的进展
4. LncRNA GAS5 Inhibits Progression of Colorectal Cancer by Regulating M1/M2 Macrophages Polarization [C] . Linyu Tang, Quanpeng Li, Xianxiu Ge, International Symposium on the Frontiers of Biotechnology and Bioengineering . 2019

机译：通过调节M1 / M2巨噬细胞极化，LNCRNA Gas5抑制结肠直肠癌的进展
5. Functional role of a Ewing-sarcoma-specific vlncRNA in tumor growth and progression. [D] . Liu, Yang. 2016

机译：尤文肉瘤特异性vlncRNA在肿瘤生长和进展中的功能作用。
6. LncRNA RMRP silence curbs neonatal neuroblastoma progression by regulating microRNA-206/tachykinin-1 receptor axis via inactivating extracellular signal-regulated kinases [O] . Juntao Pan, Da Zhang, Jiao Zhang, 2019

机译：LncRNA RMRP沉默通过灭活细胞外信号调节激酶来调节microRNA-206 / tachykinin-1受体轴从而抑制新生儿神经母细胞瘤的发展
7. HOXD-AS1 is a novel lncRNA encoded in HOXD cluster and a marker of neuroblastoma progression revealed via integrative analysis of noncoding transcriptome [O] . Aliaksandr A Yarmishyn, Arsen O Batagov, Jovina Z Tan, 2014

机译：HOXD-AS1是在HOXD簇中编码的新型lncRNA，是通过对非编码转录组进行综合分析揭示的神经母细胞瘤进展的标志物
8. Identifying microRNAs that Regulate Neuroblastoma Cell Differentiation. [R] . Du, L. 2015

机译：鉴定调节神经母细胞瘤细胞分化的微小RNa。

LncRNAs join hands together to regulate neuroblastoma progression

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