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Update on Cryptosporidium spp.: highlights from the Seventh International Giardia and Cryptosporidium Conference

机译:隐孢子虫属的更新:第七届国际贾第虫和隐孢子虫会议的要闻

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摘要

While cryptosporidiosis is recognized as being among the most common causes of human parasitic diarrhea in the world, there is currently limited knowledge on infection mechanisms, incomplete codification of diagnostic methods, and a need for additional therapeutic options. In response, the Seventh International and Conference (IGCC 2019) was hosted from 23 to 26 June 2019, at the Rouen Normandy University, France. This trusted event brought together an international delegation of researchers to synthesize recent advances and identify key research questions and knowledge gaps. The program of the interdisciplinary conference included all aspects of host-parasite relationships from basic research to applications to human and veterinary medicine, and environmental issues associated with waterborne parasites and their epidemiological consequences. In relation to and cryptosporidiosis, the primary research areas for which novel findings and the most impressive communications were presented and discussed included: in environmental waters, seafood, and fresh produce; Animal epidemiology; Human cryptosporidiosis and epidemiology; Genomes and genomic evolution encompassing: Comparative genomics of spp., Genomic insights into biology, Acquiring and utilizing genome sequences, Genetic manipulation; Host-parasite interaction (immunology, microbiome); and Diagnosis and treatment. High quality presentations discussed at the conference reflected decisive progress and identified new opportunities that will engage investigators and funding agencies to spur future research in a “one health” approach to improve basic knowledge and the clinical and public health management of zoonotic cryptosporidiosis.
机译:尽管隐孢子虫病被认为是世界上人类寄生虫性腹泻的最常见原因,但目前对感染机制,诊断方法的不完整编码以及对其他治疗选择的了解有限。作为回应,第七届国际会议(IGCC 2019)于2019年6月23日至26日在法国鲁昂诺曼底大学举行。这项值得信赖的活动汇聚了一个国际研究人员代表团,以综合最新进展并确定关键的研究问题和知识差距。跨学科会议的方案包括寄主-寄生虫关系的各个方面,从基础研究到对人类和兽医学的应用,以及与水生寄生虫有关的环境问题及其流行病学后果。关于和隐孢子虫病,提出和讨论了新发现和最令人印象深刻的交流的主要研究领域包括:环境水,海鲜和新鲜农产品;动物流行病学;人类隐孢子虫病和流行病学;基因组和基因组进化,包括:spp。的比较基因组学,生物学的基因组学见识,基因组序列的获取和利用,遗传操作;宿主-寄生虫相互作用(免疫学,微生物组);和诊断和治疗。会议上讨论的高质量演讲反映了决定性的进展,并确定了新的机会,将吸引研究者和资助机构以“一种健康”的方式刺激未来的研究,以改善人畜共患隐孢子虫病的基础知识以及临床和公共卫生管理。

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