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Influence of Vegetarian Dietary Intervention on Urinary Paraben Concentrations: A Pilot Study with ‘Temple Stay’ Participants

机译:素食饮食干预对尿液中对羟基苯甲酸酯浓度的影响:天宫参与者的初步研究

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摘要

Personal care products and cosmetics have been identified as major sources of paraben exposure among humans. However, the contribution of dietary factors has not been well understood. We recruited temple stay participants ( = 25) who followed a strict Buddhist vegetarian diet during a five-day period, and assessed the influence of this lifestyle change, employing their urine samples collected before and after the temple stay. Before the temple stay, methylparaben (MeP) was detected at the highest levels, followed by ethylparaben (EtP), propylparaben (PrP), butylparaben (BuP), and benzophenones (BPs) in the urine samples. Following the temple stay, the urinary EtP concentrations remarkably increased from 14.0 to 105 μg/L, and were around two orders of magnitude higher than those reported from other countries. Dietary factors associated with the temple diet may partly explain the increase, because EtP is allowed in Korea for seasoning and condiments, which are frequently added in vegetarian diets. Following the temple stay, however, MeP, PrP, and BPs did not show significant decreasing trends. In contrast, BuP levels decreased significantly, especially in male urine samples, that is, from 3.60 to 1.03 μ/L, suggesting a reduced use of certain personal care products during the temple stay. Our observations outline the potential importance of dietary factors on EtP exposure, and might help explain its high exposure levels among Korean population.
机译:个人护理产品和化妆品已被确定为人类对羟基苯甲酸酯暴露的主要来源。但是,饮食因素的作用还没有被很好地理解。我们招募了寺庙住所参与者(= 25),他们在五天的时间内严格遵守佛教素食饮食,并使用他们在寺庙住所前后收集的尿液样本评估了这种生活方式变化的影响。在寺庙停留之前,尿液样品中检出的对羟基苯甲酸甲酯(MeP)含量最高,其次是对羟基苯甲酸乙酯(EtP),对羟基苯甲酸丙酯(PrP),对羟基苯甲酸丁酯(BuP)和二苯甲酮(BPs)。停留在太阳穴后,尿中的EtP浓度从14.0显着增加到105μg/ L,比其他国家报告的高出两个数量级。与寺庙饮食有关的饮食因素可以部分解释这一增加,因为韩国允许将EtP用作调味料和调味品,而素食主义者经常添加这些调味品和调味品。但是,在太阳穴停留后,MeP,PrP和BP并没有显示出明显的下降趋势。相反,BuP水平显着降低,尤其是在男性尿液样本中,从3.60降低至1.03μ/ L,这表明在寺庙逗留期间减少使用某些个人护理产品。我们的观察结果概述了饮食因素对EtP暴露的潜在重要性,并可能有助于解释其在韩国人群中的高暴露水平。

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