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Study of Antioxidant Activity of Some Medicinal Plants Having High Content of Caffeic Acid Derivatives

机译:一些高咖啡酸衍生物含量的药用植物的抗氧化活性研究

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摘要

Recently, there has been increasing interest in medicinal plants, due to their content of health-promoting compounds, e.g., caffeic acids derivatives. Hence, the aim of this work was to study the antioxidant activity of extracts obtained from the following medicinal plants: caraway ( L.), coltsfoot ( L.), dandelion ( F.H.Wigg.), lovage ( L.), tarragon ( L.) and white mulberry ( L.), characterized by their high content of caffeic acid derivatives. The water-ethanolic extracts were characterized on average by about 9 times higher contents of caffeic acid derivatives level than water extracts. Both in water and water-ethanolic extracts, the dominant phenolic acid was 5-CQA (5- -caffeoylquinic acid) and 3,4-diCQA (3,4-dicaffeoylquinic acid), then CCA-1 (chicoric acid isomer 1), which appeared only in water-ethanolic extracts. Extracts from dandelion contained compounds such as CTA (caftaric acid), CCA-1 (chicoric acid isomer 1) and CCA-2 (chicoric acid isomer 2), which were not detected in other plant extracts examined in this work. The water-ethanolic extracts from coltsfoot and tarragon were characterized by a high content of di-caffeoylquinic acids, especially 3,4-diCQA and 3,5-diCQA, respectively. It has been stated that there is a positive correlation between caffeic acid derivatives and antioxidant activity (radical cation scavenging activity (ABTS) and radical scavenging activity (DPPH)), especially in water-ethanolic extract of medicinal plants.
机译:近来,由于药用植物中促进健康的化合物例如咖啡酸衍生物的含量,对药用植物的兴趣日益增加。因此,这项工作的目的是研究从以下药用植物中提取的提取物的抗氧化活性:香菜(L.),款冬(L.),蒲公英(FHWigg。),独活草(L.),龙蒿(L. 。)和桑(L.),其特征在于咖啡酸衍生物含量高。水-乙醇提取物的特征在于平均咖啡酸衍生物含量比水提取物高约9倍。在水提取物和水乙醇提取物中,主要的酚酸是5-CQA(5--咖啡酰奎尼酸)和3,4-diCQA(3,4-二咖啡酰奎尼酸),然后是CCA-1(癸二酸异构体1),仅出现在水-乙醇提取物中。蒲公英的提取物中含有诸如CTA(咖啡酸),CCA-1(衣康酸异构体1)和CCA-2(衣康酸异构体2)之类的化合物,在本工作中研究的其他植物提取物中均未检出。来自款冬和龙蒿的水-乙醇提取物的特征在于高含量的二咖啡酰奎尼酸,尤其是分别为3,4-diCQA和3,5-diCQA。已经指出,咖啡酸衍生物与抗氧化剂活性(自由基阳离子清除活性(ABTS)和自由基清除活性(DPPH))之间存在正相关,尤其是在药用植物的水-乙醇提取物中。

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