• 主题
高级搜索  >
历史搜索 清空历史
首页> 美国卫生研究院文献>Journal of Clinical Research in Pediatric Endocrinology >Maternal and Neonatal Urinary Iodine Status and its Effect on Neonatal TSH Levels in a Mildly Iodine-Deficient Area
【2h】

Maternal and Neonatal Urinary Iodine Status and its Effect on Neonatal TSH Levels in a Mildly Iodine-Deficient Area

机译：轻度缺碘地区孕妇和新生儿尿碘状况及其对新生儿TSH水平的影响

代理获取
本网站仅为用户提供外文OA文献查询和代理获取服务，本网站没有原文。下单后我们将采用程序或人工为您竭诚获取高质量的原文，但由于OA文献来源多样且变更频繁，仍可能出现获取不到、文献不完整或与标题不符等情况，如果获取不到我们将提供退款服务。请知悉。
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

>Objective: Iodine deficiency and excess are the most important factors that affect screening and recall rates of congenital hypothyroidism. The purpose of this study was to investigate the urinary iodine status in newborns and their mothers and its effects on neonatal thyroid-stimulating hormone (TSH) levels in a mildly iodine-deficient area.>Methods: A total of 116 newborns and their mothers were included in the study. Urinary iodine levels were measured from healthy mothers and their babies on the 5th day following birth. Neonatal TSH levels were screened, and TSH and free thyroxine (fT4) levels were measured on the15th day in the recall cases. T4 treatment was started in infants with high TSH and low fT4 levels. These measurements were repeated on the 30th day in these newborns.>Results: Ninety-nine percent of the mothers included in the study were using iodized salt. The median urinary iodine level in the newborns was 279 µg/L, while it was 84 µg/L in their mothers. The rate of iodine deficiency among the mothers was 56.8%, and the rate of iodine excess was 8.6%. This rate was 10.3% for iodine deficiency and 61.2% for iodine excess in the newborns. The recall rate at the screening was 9.5% (n=11). The urinary iodine levels were above 200 µg/L in three newborns who had transient hyperthyrotropinemia.>Conclusions: Iodine deficiency was more frequently observed in nursing mothers, and iodine excess was more frequently seen in their newborns. The iodine excess noted in the newborns was attributed to the use of antiseptics containing iodine. The iodine excess leads to increases in recall rates, screening costs, and frequency of transient hyperthyrotropinemia.>Conflict of interest:None declared.
机译：>目的：碘缺乏和过量是影响先天性甲状腺功能减退症筛查和召回率的最重要因素。这项研究的目的是调查轻度缺碘地区新生儿及其母亲的尿碘状况及其对新生儿甲状腺刺激激素（TSH）水平的影响。>方法：该研究包括116名新生儿及其母亲。在出生后第5天从健康的母亲及其婴儿中测量尿碘水平。在召回病例的第15天，筛查新生儿TSH水平，并测量TSH和游离甲状腺素（fT4）水平。高TSH和低fT4水平的婴儿开始T4治疗。在这些新生儿的第30天重复进行这些测量。>结果：研究中包括的母亲中有99％使用了碘盐。新生儿中的尿碘中位数为279 µg / L，而其母亲为84 µg / L。母亲中碘缺乏症的发生率为56.8％，而碘过量的发生率为8.6％。新生儿缺碘的发生率为10.3％，碘过量的发生率为61.2％。筛查的召回率为9.5％（n = 11）。三个短暂性甲状腺素过高症新生儿的尿碘水平高于200 µg / L。>结论：在哺乳母亲中碘缺乏症发生率更高，在新生儿中碘过多的发生率更高。新生儿中碘的过量归因于使用了含碘的防腐剂。碘过量会导致召回率，筛查成本和短暂性甲状腺素过高血症的发生频率增加。>利益冲突：未宣布。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
代理获取

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号