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首页> 美国卫生研究院文献>Developmental Cognitive Neuroscience >Developmental changes in brain response to speech perception in late-talking children: A longitudinal MMR study
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Developmental changes in brain response to speech perception in late-talking children: A longitudinal MMR study

机译：晚期说话儿童大脑对言语感知的反应发育变化：纵向MMR研究

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This study used a longitudinal design to examine the development of mismatch responses (MMRs) to Mandarin lexical tones, an index of neural speech discriminative responses, in late talkers and typical controls at 3, 5, and 6 years of age. Lexical tones are phonetic suprasegments that distinguish the lexical meanings of syllables in tonal languages. The 2 year-old late talkers were later divided into persistent language delay and late bloomer groups according to their performance on standardized language tests at 4 years. Results showed that children with persistent language delay demonstrated more positive mismatch responses than the typical controls at 3 years of age. At the age of 5, no group difference were found in the amplitude of MMRs, but the maturation of MMRs could be observed in the change of topography, with more prominent negative response in the frontal sites only in the typical group. Correlations were found between the index of MMRs at 3 years and children’s language performance outcome at 6 years. Our results indicate that the development of fine-grained tone representations is delayed in late-talking children between 3 and 5 years and may be one of the underlying mechanisms which associated with later language performance.
机译：这项研究使用纵向设计来检查在3、5和6岁年龄段的晚期说话者和典型对照者对普通话词汇音调的失配反应（MMR）的发展，这是神经语音歧视反应的指标。词汇音调是语音上调，可区分音调语言中音节的词汇含义。根据他们在4年的标准化语言测试中的表现，将这两个2岁的晚说话者后来分为持续的语言延迟和晚布鲁姆组。结果显示，持续性语言延迟的儿童比3岁的典型对照组表现出更多的积极错配反应。在5岁时，没有发现MMR幅度的组差异，但是在地形变化中可以观察到MMR的成熟，仅在典型组中额叶部位的负反应更为明显。在3岁时的MMR指数与6岁时的儿童语言表现结果之间存在相关性。我们的结果表明，细语调表示的发展在3到5岁之间的较晚说话的儿童中被延迟了，这可能是与后来的语言表现相关的潜在机制之一。

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