首页> 美国卫生研究院文献>Iranian Journal of Pharmaceutical Research : IJPR >Determination of Mirtazapine and Desmethyl Mirtazapine in Human Plasma by a New Validated HPLC Ultraviolet Method with a Simple and Reliable Extraction Method: Application to Therapeutic Drug Monitoring Study by 62 Real Patient Plasma

【2h】

Determination of Mirtazapine and Desmethyl Mirtazapine in Human Plasma by a New Validated HPLC Ultraviolet Method with a Simple and Reliable Extraction Method: Application to Therapeutic Drug Monitoring Study by 62 Real Patient Plasma

机译：一种新的验证的HPLC紫外法测定人血浆中的植物血浆和去甲基甲脒具有简单可靠的萃取方法：62个真实患者血浆的治疗药物监测研究应用

代理获取

本网站仅为用户提供外文OA文献查询和代理获取服务，本网站没有原文。下单后我们将采用程序或人工为您竭诚获取高质量的原文，但由于OA文献来源多样且变更频繁，仍可能出现获取不到、文献不完整或与标题不符等情况，如果获取不到我们将提供退款服务。请知悉。

页面导航

摘要
著录项
相似文献
相关主题

摘要

Determination of mirtazapine (MRP) during psychopharmacotherapy in biological fluids is essential to achieve successful therapy, to avoid toxicity related to drug interactions, genetic variability, and poor compliance. A new, rapid, and sensitive high-performance liquid chromatography method has been developed in human plasma for the determination of MRP and -desmethylmirtazapine (NDM) that is an active metabolite.

机译：在生物液中的精神药物疗法期间测定mirtazapine（MRP）对于实现成功疗法至关重要，以避免与药物相互作用，遗传变异性和依从性差相关的毒性。在人血浆中开发了一种新的，快速和敏感的高效液相色谱法，用于测定作为活性代谢物的MRP和-DESMIRTAZAPINE（NDM）。

著录项

期刊名称 Iranian Journal of Pharmaceutical Research : IJPR
作者
Emrah Dural; Nilay Sedes Baskak; Hatice Özcan; Yağmur Kır; Bora Başkak; Halil Sinan Süzen;
展开▼
作者单位

展开▼
年(卷),期 2020(19),1
年度 2020
页码 -1
总页数 13
原文格式 PDF
正文语种
中图分类药学;
关键词
Mirtazapine; N-desmethylmirtazapine; Plasma; HPLC-UV; Therapeutic drug monitoring; Validation;

相似文献

外文文献
中文文献
专利

1. Simple HPLC Method for Quantitative Determination of Carbinoxamine in Human Plasma: Application in Pharmacokinetic Studies and Therapeutic Drug Monitoring [J] . Soha M. El-Masry, Rasha M. El-Morsi Drug research . 2019,第6期

机译：人血浆中碳甲胺定量测定的简单HPLC方法：在药代动力学研究和治疗药物监测中的应用
2. A fast, sensitive and simple method for mirtazapine quantification in human plasma by HPLC-ESI-MS/MS. Application to a comparative bioavailability study [J] . BorgesN.C., Barrientos-AstigarragaR.E., SverdloffC.E., Biomedical Chromatography: An International Journal Devoted to Research in Chromatographic Methodologies and Their Applications in the Biosciences . 2012,第11期

机译：通过HPLC-ESI-MS / MS快速，灵敏和简单的方法测定人血浆中的米氮平。在比较生物利用度研究中的应用
3. A validated liquid chromatographic tandem mass spectrometric method for the determination of mirtazapine and demethylmirtazapine in human plasma:application to a pharmacokinetic study [J] . Constantinos Pistos, Maria Koutsopoulou, Irene Panderi Analytica chimica acta . 2004,第1期

机译：经验证的液相色谱串联质谱法测定人血浆中的米氮平和去甲基米氮平：在药代动力学研究中的应用
4. Validation of Pyrazinamide in Human Plasma Using Hplc-Uv for Therapeutic Drug Monitoring [C] . E. Mulyani, E. Darmawan, D.A. Perwitasari, Conference on Fundamental and Applied Science for Advanced Technology . 2016

机译：HPLC-UV治疗药物监测验证人血浆中吡嗪酰胺的验证
5. Method development and validation for the determination of Mirtazapine and Warfarin in the raw material using polar phase liquid phase high performance liquid chromatography. [D] . Hanini, Nermein. 2016

机译：极性相液相高效液相色谱法测定原料中的米氮平和华法林的方法开发和验证。
6. A Rapid and Sensitive HPLC-Fluorescence Method for Determination of Mirtazapine and Its two Major Metabolites in Human Plasma [O] . Hoda Lavasani, Mario Giorgi, Behjat Sheikholeslami, 2014

机译：快速灵敏的高效液相色谱-荧光法测定人血浆中的米氮平及其两种主要代谢物
7. Rapid and sensitive liquid chromatography–tandem mass spectrometry method for determination of 1-β-d-arabinofuranosyluracil in human plasma and application to therapeutic drug monitoring in patient with leukemia [O] . Liao Chuanrong, Chang Sheng, Hu Shuhua, 2013

机译：快速灵敏的液相色谱-串联质谱法测定人血浆中的1-β-d-阿拉伯呋喃糖基尿嘧啶及其在白血病患者治疗药物监测中的应用

Determination of Mirtazapine and Desmethyl Mirtazapine in Human Plasma by a New Validated HPLC Ultraviolet Method with a Simple and Reliable Extraction Method: Application to Therapeutic Drug Monitoring Study by 62 Real Patient Plasma

摘要

著录项

相似文献

相关主题

期刊订阅