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首页> 美国卫生研究院文献>Antibiotics >Incorporation of Hybrid Nanomaterial in Dental Porcelains: Antimicrobial Chemical and Mechanical Properties
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Incorporation of Hybrid Nanomaterial in Dental Porcelains: Antimicrobial Chemical and Mechanical Properties

机译：在牙科瓷器中掺入杂交纳米材料：抗微生物化学和机械性能

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Biofilm formation on biomaterials is a challenge in the health area. Antimicrobial substances based on nanomaterials have been proposed to solve this problem. The aim was to incorporate nanostructured silver vanadate decorated with silver nanoparticles (β-AgVO3) into dental porcelains (IPS Inline and Ex-3 Noritake), at concentrations of 2.5% and 5%, and evaluate the surface characteristics (by SEM/EDS), antimicrobial activity (against Streptococcus mutans, Streptococcus sobrinus, Aggregatibacter actinomycetemcomitans, and Pseudomonas aeruginosa), silver (Ag+) and vanadium (V4+/V5+) ions release, and mechanical properties (microhardness, roughness, and fracture toughness). The β-AgVO3 incorporation did not alter the porcelain’s components, reduced the S. mutans, S. sobrinus and A. actinomycetemcomitans viability, increased the fracture toughness of IPS Inline, the roughness for all groups, and did not affect the microhardness of the 5% group. Among all groups, IPS Inline 5% released more Ag+, and Ex-3 Noritake 2.5% released more V4+/V5+. It was concluded that the incorporation of β-AgVO3 into dental porcelains promoted antimicrobial activity against S. mutans, S. sobrinus, and A. actinomycetemcomitans (preventing biofilm formation), caused a higher release of vanadium than silver ions, and an adequate mechanical behavior was observed. However, the incorporation of β-AgVO3 did not reduce P. aeruginosa viability and increased the surface roughness of dental porcelains.
机译：生物材料的生物膜形成是健康区的挑战。已经提出了基于纳米材料的抗微生物物质来解决这个问题。目的是将用银纳米粒子（β-AGVO3）装饰的纳米结构化银钒酸盐掺入牙科瓷（IPS内联和EX-3 Noritake），浓度为2.5％和5％，评价表面特性（通过SEM / EDS） ，抗菌活性（对抗链球菌，链球菌，Sobrinus，聚糖杆菌菌，铜绿假单胞菌），银（Ag +）和钒（V4 + / v5 +）离子释放，以及机械性能（微硬度，粗糙度和断裂韧性）。 β-agvo3掺入没有改变瓷器的组分，降低了S. mutans，S. sobrinus和A. actinomycetemcolans的活力，增加了IP的骨折韧性，所有群体的粗糙度，并没有影响5的微硬度％ 团体。在所有群体中，IPS内联5％释放了更多AG +，EX-3 Noritake 2.5％释放了更多V4 + / V5 +。得出结论，将β-Agvo3掺入牙科瓷中，促进了对S. mutans，S. sobrinus和A. actinomycetemcoNs（防止生物膜形成）的抗微生物活性，导致钒的含量高于银离子，以及足够的机械行为被观测到。然而，β-AGVO3的掺入没有降低铜绿假单胞菌的活力并增加牙科瓷的表面粗糙度。

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