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Discovery validation and sequencing of urinary peptides for diagnosis of liver fibrosis—A multicentre study

机译：泌尿肽诊断肝纤维化诊断的发现验证和测序 - 多期几项研究

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摘要

Liver fibrosis is a consequence of chronic inflammation and is associated with protein changes within the hepatocytes structure. In this study, we aimed to investigate if this is reflected by the urinary proteome and can be explored to diagnose liver fibrosis in patients with chronic liver disease.

机译：肝纤维化是慢性炎症的结果，并且与肝细胞结构内的蛋白质变化有关。在这项研究中，我们旨在调查这一点是否反映了尿蛋白质，可以探索患有慢性肝病患者的肝纤维化。

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期刊名称 EBioMedicine
作者
Ayman S. Bannaga; Jochen Metzger; Ioannis Kyrou; Torsten Voigtländer; Thorsten Book; Jesus Melgarejo; Agnieszka Latosinska; Martin Pejchinovski; Jan A. Staessen; Harald Mischak; Michael P. Manns; Ramesh P. Arasaradnam;
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年(卷),期 2020(-1),-1
年度 2020
页码 -1
总页数 12
原文格式 PDF
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中图分类
关键词
Liver fibrosis; Capillary electrophoresis mass spectrometry; Urinary peptide marker; Diagnosis;

机译：肝纤维化;毛细管电泳质谱;尿肽标记;诊断;

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专利

1. Discovery, validation and sequencing of urinary peptides for diagnosis of liver fibrosis—A multicentre study [J] . Ayman S. Bannaga, Jochen Metzger, Ioannis Kyrou, EBioMedicine . 2020,第6期

机译：泌尿肽诊断肝纤维化诊断的发现，验证和测序 - 多期几项研究
2. European multicentre study validates enhanced liver fibrosis test as biomarker of fibrosis in systemic sclerosis [J] . Abignano Giuseppina, Blagojevic Jelena, Bissell Lesley-Anne, Rheumatology . 2019,第2期

机译：欧洲多期体研究验证了增强的肝纤维化试验作为全身硬化症纤维化的生物标志物
3. CYSTIC FIBROSIS URINARY BIOMARKER STUDY: A MULTICENTRE LONGITUDINAL STUDY AIMED AT DISCOVERING URINARY BIOMARKERS OF LUNG INJURY IN CHILDREN WITH CF [J] . Al-Shidhani K., Reilly R., Parekh G., Pediatric Pulmonology . 2018,第Suppla2期

机译：囊性纤维化尿生物标志物研究：多期纵向研究，旨在发现CF儿童肺损伤的尿生物标志物
4. Association between Liver Function, Hepatic Fibrosis Index and Urinary Thiodiglycolic Acid in School-Aged Children Living near a Petrochemical Complex [C] . Po-Chin Huang, Chih Wen Wang, Kai-Wei Liao, Joint annual meeting of the International Society of Exposure Science and the International Society for Environmental Epidemiology . 2018

机译：居住在石化厂附近的学龄儿童肝功能，肝纤维化指数和尿巯基乙醇酸之间的关系
5. De novo peptide sequencing of spider silk proteins by mass spectrometry and discovery of novel fibroin genes [D] . Hu, Xiaoyi 2004

机译：质谱从头对蜘蛛丝蛋白进行从头测序并发现新的丝蛋白基因
6. Multicentre prospective validation of a urinary peptidome-based classifier for the diagnosis of type 2 diabetic nephropathy [O] . Justyna Siwy, Joost P. Schanstra, Angel Argiles, -1

机译：基于尿肽组的分类器对2型糖尿病肾病的诊断的多中心前瞻性验证
7. Discovery, validation and sequencing of urinary peptides for diagnosis of liver fibrosis—A multicentre study [O] . Ayman S. Bannaga, Jochen Metzger, Ioannis Kyrou, 2020

机译：泌尿肽诊断肝纤维化诊断的发现，验证和测序 - 多期几项研究

Discovery validation and sequencing of urinary peptides for diagnosis of liver fibrosis—A multicentre study

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