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Nutrition the digestive system and immunity in COVID-19 infection

机译:Covid-19感染中的消化系统和免疫力营养消化系统和免疫力

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摘要

The current review aimed to synthesize the literature on the complex relationship between food consumption and nutritional status as well as the digestive system in order to examine the relationship between immunity and potential responses to COVID-19 infection. The goal is to help inform the many healthcare professionals working with COVID-19 patients. A literature search was performed on PubMed, Scopus, and EMBASE databases. Hand searches were also undertaken using Google and reference lists to identify recent evidence. Studies were critically appraised, and the findings were analyzed by narrative synthesis. Nutritional status can impact immunity in several ways, including affecting susceptibility to infection, severity of disease, and recovery time, and is therefore a significant consideration in the management of COVID-19. COVID-19 can also impact digestive function, which can further impact nutritional status. The role of Vitamin D deficiency in vulnerability to severe respiratory infections, including COVID-19, has been recognized, and it may have a role in treatment where deficiency is indicated. Healthcare professionals should be aware that obesity may be accompanied by micronutrient malnutrition including vitamin D deficiency and alterations in the microbiome and inflammatory responses, which can further impact immunity and disease severity. Multidisciplinary team-work is recommended in the management of patients with COVID-19, and approaches should include a consideration of nutritional status (both macronutrients and micronutrients), body weight, and gastrointestinal signs and symptom.
机译:目前的审查旨在综合食品消费与营养状况与消化系统之间的复杂关系的文献,以检查免疫力与对Covid-19感染的潜在反应之间的关系。目标是帮助通知许多医疗保健专业人员与Covid-19患者合作。在PubMed,Scopus和Embase数据库上执行文献搜索。还使用Google和Reference列表进行手中搜索来确定最近的证据。研究受到严重评估,并通过叙事合成分析了研究结果。营养状况可能会以多种方式影响免疫力,包括影响对感染,疾病严重程度和恢复时间的易感性,因此在Covid-19管理方面是一个重要的考虑因素。 Covid-19还可以影响消化功能,这可以进一步影响营养状况。已经认识到维生素D缺乏缺乏缺乏在脆弱性对严重呼吸道感染的作用,并且已经认识到包括Covid-19,并且在指示缺乏的治疗中可能存在作用。医疗保健专业人员应该意识到肥胖症可以伴有微量营养素营养不良,包括维生素D缺乏和微生物组和炎症反应的变化,这可以进一步影响免疫和疾病严重程度。在Covid-19患者管理中建议多学科团队工作,方法应包括营养状况(Macronurivers和微量营养素),体重和胃肠道标志和症状的审议。

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