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首页> 美国卫生研究院文献>International Journal of Environmental Research and Public Health >Predictors of New Dementia Diagnoses in Elderly Individuals: A Retrospective Cohort Study Based on Prefecture-Wide Claims Data in Japan
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Predictors of New Dementia Diagnoses in Elderly Individuals: A Retrospective Cohort Study Based on Prefecture-Wide Claims Data in Japan

机译：老年人诊断新痴呆症诊断的预测因素：基于县域索赔数据的回顾队列研究

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摘要

Preventing dementia in elderly individuals is an important public health challenge. While early identification and modification of predictors are crucial, predictors of dementia based on routinely collected healthcare data are not fully understood. We aimed to examine potential predictors of dementia diagnosis using routinely collected claims data. In this retrospective cohort study, claims data from fiscal years 2012 (baseline) and 2016 (follow-up), recorded in an administrative claims database of the medical care system for the elderly (75 years or older) in Niigata prefecture, Japan, were used. Data on baseline characteristics including age, sex, diagnosis, and prescriptions were collected, and the relationship between subsequent new diagnoses of dementia and potential predictors was examined using multivariable logistic regression models. A total of 226,738 people without a diagnosis of dementia at baseline were followed. Of these, 26,092 incident dementia cases were detected during the study period. After adjusting for confounding factors, cerebrovascular disease (odds ratio, 1.15; 95% confidence interval, 1.11–1.18), depression (1.38; 1.31–1.44), antipsychotic use (1.40; 1.31–1.49), and hypnotic use (1.17; 1.11–1.24) were significantly associated with subsequent diagnosis of dementia. Analyses of routinely collected claims data revealed neuropsychiatric symptoms including depression, antipsychotic use, hypnotic use, and cerebrovascular disease to be predictors of new dementia diagnoses.
机译：预防老年人的痴呆症是一个重要的公共卫生挑战。虽然预测器的早期识别和修改是至关重要的，但基于常规收集的医疗保健数据的痴呆预测因子都没有完全理解。我们旨在使用常规收集的权利要求来检查痴呆症诊断的潜在预测因子。在这个回顾性的队列研究中，在日本新泻县的老年人（75岁或以上）的行政索赔数据库中记录的2012财年（基线）和2016（随访）的声称数据是日本的用过的。收集了基线特征的数据，包括年龄，性别，诊断和处方，以及随后的痴呆症和潜在预测因子之间的关系进行了使用多变量逻辑回归模型。随后，共有226,738人没有诊断基线痴呆症。其中，在研究期间检测到26,092例入射痴呆病例。调整混淆因子后，脑血管病（差距，1.15; 95％; 1.11-1.18），抑郁（1.38; 1.31-1.44），抗精神用使用（1.40; 1.31-1.49）和催眠用途（1.17; 1.11 -1.24）与随后的痴呆诊断有显着相关。常规收集的权利要求数据分析显示神经精神症状，包括抑郁，抗精神用，催眠用途和脑血管疾病，以预测新的痴呆症诊断。

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