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首页> 美国卫生研究院文献>Journal of Animal Science and Technology >Influences of dietary flavonoid (quercetin) supplementation on growthperformance and immune response of growing pigs challenged with
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Influences of dietary flavonoid (quercetin) supplementation on growthperformance and immune response of growing pigs challenged with

机译：膳食黄酮（槲皮素）对生长的影响生长猪挑战的性能和免疫应答

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This study was conducted to evaluate the effects of dietary supplementation ofplant flavonoid (quercetin) on immune parameters, growth performance, andnutrient digestibility in growing pigs challenged with Escherichiacoli lipopolysaccharide (LPS). A total of 40 crossbred ([Landrace× Yorkshire] × Duroc) growing pigs; initial body weight (BW) of26.95 ± 1.26 kg were used in a six-week experimental trial. Pigs wererandomly allocated into one of four treatment groups in a 2 × 2 factorialarrangement with the following factors; without LPS challenge and with LPSchallenge (day 21) supplemented with or without 0.1% flavonoid according to BW(2 replicate pens per treatment with 2 gilts and 3 barrows per pen). The single-dose LPS (100 ug / kg BW) injection showed trends tended to be increased ininterleukin-6 (IL-6) after 2 h and 6 h of challenge compared with unchallengedpigs. However, other measured immune indices (white blood cell, immunoglobulinG, lymphocyte, and tumor necrosis factor), growth performance, and nutrientdigestibility were not significantly different between challenged andnon-challenged animals. The supplementation of flavonoid significantly increased(p < 0.05) average daily gain (ADG) during day0–21, tended to increase dry matter and nitrogen digestibility,significantly reduced IL-6, increased Ig-G and WBC concentrations and increasedlymphocytes percentage regardless of LPS challenge.
机译：本研究进行了评估膳食补充的影响植物黄酮（槲皮素）免疫参数，生长性能和生长猪的营养消化率与大肠杆菌挑战大胆脂多糖（LPS）。共有40个杂交（[Landrace×约克夏]×Duroc）种植猪;初始体重（BW）在六周的实验试验中使用26.95±1.26千克。猪是随机分配到2×2因子中的四个治疗组中的一个安排以下因素;没有LPS挑战和LPS根据BW补充有或没有0.1％黄酮类化合物的挑战（第21天）（2每处理钢笔2吉尔，每支笔是3个猎犬）。单一的剂量LPS​​（100ug / kg bw）注射显示趋势趋于增加白细胞介素-6（IL-6）与未经充电相比，2小时和6小时后猪。但是，其他测量的免疫指数（白细胞，免疫球蛋白g，淋巴细胞和肿瘤坏死因子），生长性能和营养素攻击性和挑战性之间的消化率没有显着差异非挑战动物。补充黄酮类化合物显着增加（P <0.05）白天平均每日增益（ADG）0-21，倾向于增加干物质和氮气消化率，显着降低IL-6，增加Ig-G和WBC浓度并增加无论LPS挑战如何，淋巴细胞百分比。

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