Fetal Cerebral Oxygenation Is Impaired in Congenital Heart Disease and Shows Variable Response to Maternal Hyperoxia

机译：胎儿脑氧合在先天性心脏病中受到损害并显示对母体高氧的可变响应

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Impairments in fetal oxygen delivery have been implicated in brain dysmaturation seen in congenital heart disease (CHD), suggesting a role for in utero transplacental oxygen therapy. We applied a novel imaging tool to quantify fetal cerebral oxygenation by measuring T2* decay. We compared T2* in fetuses with CHD with controls with a focus on cardiovascular physiologies (transposition or left‐sided obstruction) and described the effect of brief administration of maternal hyperoxia on T2* decay.

机译：胎儿氧递送的损伤均涉及先天性心脏病（CHD）中看到的脑呼吸困难时间，表明在子宫转染氧疗中的作用。我们应用了一种新型成像工具，通过测量T2 *衰减来量化胎儿氧化。我们将T2 *与CHD与对照组的胎儿进行比较，重点是心血管生理（转产或左侧梗阻），并描述了母体高氧的简要施用对T2 *腐烂的影响。

著录项

期刊名称 Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
作者
Shabnam Peyvandi; Duan Xu; Yan Wang; Whitnee Hogan; Anita Moon‐Grady; A. James Barkovich; Orit Glenn; Patrick McQuillen; Jing Liu;
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作者单位

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年(卷),期 2021(10),1
年度 2021
页码 e018777
总页数 17
原文格式 PDF
正文语种
中图分类心血管疾病;
关键词
brain imaging; congenital heart disease; fetal;

机译：脑成像;先天性心脏病;胎儿;

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专利

1. FETAL CEREBRAL PERFUSION AND NEONATAL CEREBRAL OXYGENATION AND SHORT TERM NEUROLOGICAL OUTCOME IN CONGENITAL HEART DISEASE [J] . Mebius M., Bilardo C., Kuik S., European journal of pediatrics . 2016,第11期

机译：先天性心脏病的胎儿脑灌注和新生儿脑氧合及短期神经功能预后
2. Hemodynamic Responses of the Placenta and Brain to Maternal Hyperoxia in Fetuses with Congenital Heart Disease by Using Blood Oxygen Level Dependent MRI [J] . You Wonsang, Andescavage Nickie N., Kapse Kushal, Radiology . 2020,第1期

机译：用血氧水平依赖MRI对先天性心脏病胎儿胎盘和胎儿对母体高氧的血流动力学响应
3. Response to Letter Regarding Article, "Reduced Fetal Cerebral Oxygen Consumption Is Associated With Smaller Brain Size in Fetuses With Congenital Heart Disease" [J] . Sun Liqun, Macgowan Christopher K., Sled John G., Circulation: An Official Journal of the American Heart Association . 2016,第1期

机译：对于有关“先天性心脏病胎儿的胎儿脑氧消耗减少与较小的大脑大小有关”的文章的答复
4. Preliminary Evaluation of Fetal Congenital Heart Defects Changes on Fetal-Maternal Heart Rate Coupling Strength [C] . Haitham M. Alangari, Yoshitaka Kimura, Ahsan H. Khandoker Annual International Conference of the IEEE Engineering in Medicine and Biology Society . 2018

机译：胎儿先天性心脏缺陷对胎儿-母亲心率耦合强度变化的初步评估
5. Genetic Interactions and Maternal Genes Modulate Congenital Heart Disease Risk [D] . Akhirome, Ehiole. 2020

机译：遗传相互作用和母体基因调节先天性心脏病风险
6. Maternal Viral Infection and Risk of Fetal Congenital Heart Diseases: A Meta‐Analysis of Observational Studies [O] . Ziwei Ye, Lesan Wang, Tubao Yang, 2019

机译：孕妇病毒感染和胎儿先天性心脏病的风险：观察性研究的荟萃分析
7. Fetal Cerebral Oxygenation Is Impaired in Congenital Heart Disease and Shows Variable Response to Maternal Hyperoxia [O] . Shabnam Peyvandi, Duan Xu, Yan Wang, 2021

机译：胎儿脑氧合在先天性心脏病中受到损害，并显示对母体高氧的可变响应

Fetal Cerebral Oxygenation Is Impaired in Congenital Heart Disease and Shows Variable Response to Maternal Hyperoxia

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