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首页> 美国卫生研究院文献>Journal of Clinical Medicine >Visual Quality and Subjective Satisfaction in Ultrathin Descemet Stripping Automated Endothelial Keratoplasty (UT-DSAEK) versus Descemet Membrane Endothelial Keratoplasty (DMEK): A Fellow-Eye Comparison
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Visual Quality and Subjective Satisfaction in Ultrathin Descemet Stripping Automated Endothelial Keratoplasty (UT-DSAEK) versus Descemet Membrane Endothelial Keratoplasty (DMEK): A Fellow-Eye Comparison

机译：超薄Descemet剥离自动内皮角膜术（UT-Dsaek）的视觉质量和主观满意度与Descemet膜内皮角膜术（DMEK）：对眼睛比较

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Background: To analyze objective and subjective visual quality differences between descemet membrane endothelial keratoplasty (DMEK) and ultra-thin descemet stripping automated endothelial keratoplasty (UT-DSAEK) with a paired contralateral-eye design. Methods: A cross-sectional, comparative, and observational case series study between DMEK and UT-DSAEK were presented. Visual acuity, refractive status and corneal quality assessment were compared between both endothelial keratoplasty techniques. The sample consisted of 20 eyes (10 patients) diagnosed with Fuchs endothelial corneal dystrophy. All measurements were performed preoperatively and at six months after surgery. Analyzed data included the measurement of objective scattering index, modulation transfer function, Strehl ratio, and optical quality assessment (OQAS) values. Contrast sensitivity, subjective patient satisfaction, visual acuity, tomography, pachymetry, endothelial cell count, and refraction status were also analyzed. Results: Objective and subjective visual quality variables had similar results among UT-DSAEK and DMEK procedures. Statistically significant differences favoring DMEK against UT-DSAEK were found in endothelial cell density (658.80 ± 139.33 and 1059.00 ± 421.84 cells/mm2, respectively), pachymetry (621.20 ± 33.74 and 529.70 ± 30.00 µm, respectively), and follow-up (45.50 ± 24.76 and 15.50 ± 8.43 months, respectively). Conclusions: UT-DSAEK and DMEK revealed no differences in terms of objective and subjective visual quality. However, DMEK showed a faster recovery during the follow-up, increased endothelial cell density, lower pachymetry, and a more anatomical posterior keratometry against UT-DSAEK in this case series paired-eye study.
机译：背景：分析DESCEMET膜内皮角膜形术（DMEK）与超薄DESCEMET剥离自动内皮角膜术（UT-DSAEK）的客观和主观视觉质量差异，具有配对对侧设计。方法：提出了DMEK和UT-DSAEK之间的横截面，比较和观察案例序列研究。在内皮角膜形型技术技术中比较了视力，屈光状态和角膜质量评估。该样品由20只眼（10名患者）组成，被诊断出患有FUCHS内皮角膜营养不良症。术前和手术后六个月进行所有测量。分析数据包括测量客观散射指数，调制传递函数，斯特勒比比和光学质量评估（OQAS）值。还分析了对比度敏感性，主观患者满意度，视力，断层扫描，偶像，内皮细胞计数和折射状态。结果：目的和主观的视觉质量变量在UT-DSAEK和DMEK程序之间具有类似的结果。对UT-DSAEK的统计学显着的差异以内皮细胞密度（658.80±139.33和1059.00±421.84个细胞/ mm2），Pachymetry（分别为621.20±33.74和529.70±30.00μm）和随访（45.50分别±24.76和15.50±8.43个月）。结论：UT-DSAEK和DMEK在客观和主观视觉质量方面没有差异。然而，DMEK在这种情况下对UT-DSAEK进行后续后续，增加的内皮细胞密度，较低的嗜睡和更具解剖学后腔测定法显示了更快的恢复。

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