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首页> 美国卫生研究院文献>Marine Drugs >Marine Pharmacology in 2016–2017: Marine Compounds with Antibacterial Antidiabetic Antifungal Anti-Inflammatory Antiprotozoal Antituberculosis and Antiviral Activities; Affecting the Immune and Nervous Systems and Other Miscellaneous Mechanisms of Action
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Marine Pharmacology in 2016–2017: Marine Compounds with Antibacterial Antidiabetic Antifungal Anti-Inflammatory Antiprotozoal Antituberculosis and Antiviral Activities; Affecting the Immune and Nervous Systems and Other Miscellaneous Mechanisms of Action

机译：2016 - 2017年海洋药理：海洋化合物具有抗菌抗糖尿病抗真菌抗炎抗促滴虫抗核酸和抗病毒活动;影响免疫和神经系统以及其他杂项行动机制

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The review of the 2016–2017 marine pharmacology literature was prepared in a manner similar as the 10 prior reviews of this series. Preclinical marine pharmacology research during 2016–2017 assessed 313 marine compounds with novel pharmacology reported by a growing number of investigators from 54 countries. The peer-reviewed literature reported antibacterial, antifungal, antiprotozoal, antituberculosis, and antiviral activities for 123 marine natural products, 111 marine compounds with antidiabetic and anti-inflammatory activities as well as affecting the immune and nervous system, while in contrast 79 marine compounds displayed miscellaneous mechanisms of action which upon further investigation may contribute to several pharmacological classes. Therefore, in 2016–2017, the preclinical marine natural product pharmacology pipeline generated both novel pharmacology as well as potentially new lead compounds for the growing clinical marine pharmaceutical pipeline, and thus sustained with its contributions the global research for novel and effective therapeutic strategies for multiple disease categories.
机译：2016-2017海洋药理文献的审查是以与本系列的最终报语类似的方式制备的。 2016 - 2017年期间的临床前海洋药理研究评估了313种海洋化合物，其中包括来自54个国家的越来越多的调查人员报告的新药理学。同行评审文献报告了123个海洋天然产物的抗菌，抗真菌，抗磷酸，抗核苷酸和抗病毒活性，111个海洋化合物，抗糖尿病和抗炎活动以及影响免疫和神经系统，同时显示出79个海洋化合物进一步调查后的杂项行动机制可能有助于几个药理课程。因此，在2016 - 2017年，临床前海洋天然产物药理学管道产生新的药理学以及普遍存在的临床海洋药物管道的潜在新的铅化合物，因此促进了对新颖和有效治疗策略的全球研究的贡献疾病类别。

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