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首页> 美国卫生研究院文献>The Journal of Clinical and Aesthetic Dermatology >Coprescription of Isotretinoin and Systemic Corticosteroids for Acne
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Coprescription of Isotretinoin and Systemic Corticosteroids for Acne

机译：异维A酸和全身性皮质类固醇共治痤疮

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>Introduction: Isotretinoin treatment has been linked to flares of severe acne, which can be managed by the coadministration of systemic corticosteroids or prevented by beginning with a low dose of isotretinoin. To our knowledge, there are no estimates in the literature on the frequency of coprescription of isotretinoin and systemic corticosteroids. >Objectives: We sought to quantify the estimated frequency of coprescription of isotretinoin and systemic corticosteroids and assess trends of the use of isotretinoin with systemic corticosteroids for acne as they relate to age, sex, race, insurance, and provider specialty. >Methods: Data from the National Ambulatory Medical Care Survey (NAMCS) from 2003 to 2015, National Hospital Ambulatory Medical Care Survey Hospital Outpatient Departments (NHAMCS-OPD) from 2003 to 2011, and National Hospital Ambulatory Medical Care Survey Hospital Emergency Departments (NHAMCS-ED) from 2003 to 2014 were aggregated for this analysis. The number of prescriptions for isotretinoin and/or systemic corticosteroids was estimated by specialty (for NAMCS) and by survey type (for NHAMCS-OPD and NHAMCS-ED). >Results: Among all first visits to a physician for acne (n=18,914,096), approximately 3.9 percent prescribed isotretinoin, 0.24 percent prescribed corticosteroids, and the remaining 96 percent prescribed neither drug. This was comparable to estimates for first visits to a dermatologist for acne (n=13,920,913), where approximately 4.2 percent prescribed isotretinoin, 0.32 percent prescribed corticosteroids, and the remaining 95 percent prescribed neither medication. >Conclusion: Currently, isotretinoin and systemic corticosteroids are rarely prescribed together.
机译：>简介：异维A酸治疗与严重痤疮发作有关，可通过全身性皮质类固醇激素合用或通过低剂量异维A酸治疗来预防。据我们所知，文献中没有关于异维A酸和全身性皮质类固醇共处方频率的估计。 >目标：我们试图量化异维A酸和全身性皮质类固醇共处方的估计频率，并评估异维A酸与全身性皮质类固醇用于痤疮的趋势，因为它们与年龄，性别，种族，保险和提供者有关专业。 >方法：数据来自2003年至2015年的国家门诊医疗调查（NAMCS），2003年至2011年的国家医院门诊医疗调查医院门诊部门（NHAMCS-OPD）和国家医院门诊医疗服务此分析汇总了2003年至2014年的调查医院急诊科（NHAMCS-ED）。异维A酸和/或全身性皮质类固醇的处方数量通过专业（针对NAMCS）和调查类型（针对NHAMCS-OPD和NHAMCS-ED）进行估算。 >结果：在所有初诊痤疮的患者中（n = 18,914,096），约3.9％的处方异维A酸，0.24％的皮质类固醇，其余96％均未使用任何药物。这与首次访问皮肤科医生治疗痤疮的估计值相当（n = 13,920,913），其中约4.2％处方了异维A酸，0.32％处方了皮质类固醇，其余95％都不使用药物。 >结论：目前，异维A酸和全身性皮质类固醇很少一起开处方。

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