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EEN Yesterday and Today … CDED Today and Tomorrow

机译:昨天和今天......今天和明天结冰了

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摘要

The treatment of Pediatric Crohn’s Disease (CD) requires attention both to achieve mucosal healing and to optimize growth, while also maintaining proper bone health. Exclusive Enteral Nutrition (EEN) is recommended as first-line treatment in luminal CD. The therapeutic mechanisms of EEN are being discovered by advances in the study of the gut microbiota. Although the total exclusion of a normal diet during the time of EEN continues to be of high importance, new modalities of dietary treatment suggest a successful future for the nutritional management of CD. In this sense, Crohn’s Disease Exclusion Diet (CDED) is a long-term strategy, it apparently acts on the mechanisms that influence the appearance of inflammation (reducing dietary exposure to products negatively affecting the microbiota), but does so using specific available whole foods to achieve this goal, increases the time of clinical remission and promotes healthy lifestyle habits. The development of CDED, which partly minimizes the problems of EEN, has enabled a turnaround in the treatment of pediatric CD. This review highlights the role of enteral nutrition in the treatment of Crohn’s disease with special emphasis on newer dietary modalities such as CDED.
机译:对儿科克罗恩病(CD)的治疗需要注意既可以达到粘膜愈合并优化生长,同时也保持适当的骨骼健康。独家肠内营养(EEN)建议作为腔夹中的一线治疗。通过肠道微生物肿瘤的研究进展来发现EEN的治疗机制。虽然在EEN的时间内排除了正常饮食的持续性高度高度,但新的饮食治疗方式表明了CD的营养管理的成功。从这个意义上讲,Crohn的疾病排斥饮食(CDED)是一个长期的策略,它显然是影响炎症外观的机制(将膳食暴露给予对微生物的产物的膳食暴露),但使用特定的可用食物为实现这一目标,增加临床缓解时间并促进健康的生活方式习惯。结垢的发展,其中部分地减少了耳膜问题,在儿科CD的治疗中使转变能够。本综述突出了肠内营养在克罗恩疾病治疗中的作用,特别强调较新的饮食方式如Caded。

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