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Chemotherapeutic drugs: Cell death- and resistance-related signaling pathways. Are they really as smart as the tumor cells?

机译：化学治疗药：细胞死亡和抵抗相关的信号通路。它们真的像肿瘤细胞一样聪明吗？

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期刊名称 Translational Oncology
作者
Mojtaba Mollaei; Zuhair Mohammad Hassan; Fatemeh Khorshidi; Ladan Langroudi;
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作者单位

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年(卷),期 2021(14),5
年度 2021
页码 101056
总页数 26
原文格式 PDF
正文语种
中图分类肿瘤学;
关键词
Chemotherapeutic drugs; Intracellular signaling; Chemoresistance; Death-related intracellular signaling; Resistance-related intracellular signaling; Combination chemotherapy; Precision medicine;

机译：化学治疗药物;细胞内信号;化学性;死亡相关的细胞内信号传导;抗性相关的细胞内信号;组合化疗;精密药物;

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专利

1. Chemotherapeutic drugs: Cell death- and resistance-related signaling pathways. Are they really as smart as the tumor cells? [J] . Mojtaba Mollaei, Zuhair Mohammad Hassan, Fatemeh Khorshidi, Translational Oncology . 2021,第5期

机译：化学治疗药：细胞死亡和抵抗相关的信号通路。它们真的像肿瘤细胞一样聪明吗？
2. Differentiation by NK cells is a prerequisite for effective targeting of cancer stem cells/poorly differentiated tumors by chemopreventive and chemotherapeutic drugs [J] . Anna Karolina Kozlowska, Paytsar Topchyan, Kawaljit Kaur, Journal of Cancer . 2017,第4期

机译：NK细胞分化是通过化学预防和化学治疗药物有效靶向癌症干细胞/低分化肿瘤的前提条件
3. CD40-mediated signaling in monocytic cells: up-regulation of tumor necrosis factor receptor-associated factor mRNAs and activation of mitogen-activated protein kinase signaling pathways. [J] . Pearson LL, Castle BE, Kehry MR International immunology. . 2001,第3期

机译：CD40介导的单核细胞信号转导：肿瘤坏死因子受体相关因子mRNA的上调和丝裂原激活的蛋白激酶信号转导途径的激活。
4. Integrin specific hydrogels as lymphoid tumors organoids for B cell receptor signaling and drug resistance [C] . Ye F Tian, Haelee Ahn, Rebecca Schneider, World biomaterials congress . 2016

机译：整联蛋白特异的水凝胶作为B细胞受体信号传导和耐药性的淋巴瘤类器官
5. Experimental chemotherapeutic approaches in solid tumor spheroids of gastro-intestinal cell lines using the chemotherapeutic drug gemcitabine-HCl (Gemzar(TM)) and the cyclooxygenase inhibitor rofecoxib (Vioxx(TM)). [D] . Intrieri, Gino. 2003

机译：使用化疗药物吉西他滨-HCl（Gemzar™）和环加氧酶抑制剂罗非考昔（Vioxx™）在胃肠道细胞系的实体肿瘤球体中进行实验性化学疗法。
6. Kinesin KIF4A is associated with chemotherapeutic drug resistance by regulating intracellular trafficking of lung resistance-related protein [O] . Li-na Pan, Yuan Zhang, Chang-jun Zhu, 2017

机译：驱动蛋白KIF4A通过调节细胞内与肺耐药性相关蛋白的运输与化疗药物耐药性相关
7. γ-Tocotrienol but Not γ-Tocopherol Blocks STAT3 Cell Signaling Pathway through Induction of Protein-tyrosine Phosphatase SHP-1 and Sensitizes Tumor Cells to Chemotherapeutic Agents* [O] . Kannappan, Ramaswamy, Yadav, Vivek R., Aggarwal, Bharat B. 2010

机译：γ-生育三烯酚而不是γ-生育酚通过诱导蛋白酪氨酸磷酸酶SHP-1阻断STAT3细胞的信号通路，并使肿瘤细胞对化学治疗剂敏感*

Chemotherapeutic drugs: Cell death- and resistance-related signaling pathways. Are they really as smart as the tumor cells?

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